Despite improvements in the therapeutic approaches for hematological malignancies in the
last decades, refractory disease still occurs, and cancer drug resistance still remains a major …

For decades, cancer biology focused largely on the protein-encoding genes that have clear
roles in tumor development or progression: cell-cycle control, apoptotic evasion, genome …

Highlights•MicroRNAs are dysregulated in acute myeloid leukemia (AML).•MicroRNA
expression profiles are useful for disease classification and prognosis.•Expression levels of …

Purpose: Uveal melanoma (UM) is characterized by multiple chromosomal rearrangements
and recurrent mutated genes. The aim of this study was to investigate if copy number …

Novel therapeutic strategies are needed for paediatric patients affected by Acute Myeloid
Leukaemia (AML), particularly for those at high-risk for relapse. MicroRNAs (miRs) have …

Background: Aberrant expression of circular RNAs (circRNAs) is tightly associated with the
pathogenesis of human cancers, including pediatric acute myeloid leukemia (AML). In this …

Background: To establish a comprehensive differential gene profile for pediatric acute
myeloid leukemia patients (pAML) based on two independent databases and verify the …

Correspondence e90© 2019 British Society for Haematology and John Wiley & Sons Ltd
British Journal of Haematology, 2020, 188, e80–e112 identification of differentially …

This study assessed whether miR-144-3p derived from BMSCs restrains the drug resistance
of AML. Our study intends to assess miR-144-3p's role in AML drug resistance. Drug …

Small non-coding RNAs (sncRNAs) are small regulatory molecules, which play key roles in
fine-tune of all cell functions. In late 1970s and early 1980s, it was first determined that non …