SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and …

L Østergaard - Physiological reports, 2021 - Wiley Online Library
Abstract Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …

[HTML][HTML] Coronary microvascular injury in myocardial infarction: perception and knowledge for mitochondrial quality control

X Chang, A Lochner, HH Wang, S Wang, H Zhu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Endothelial cells (ECs) constitute the innermost layer in all blood vessels to maintain the
structural integrity and microcirculation function for coronary microvasculature. Impaired …

The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of …

E Avolio, M Carrabba, R Milligan… - Clinical …, 2021 - portlandpress.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a broad range
of clinical responses including prominent microvascular damage. The capacity of SARS …

Coronary microvascular obstruction: the new frontier in cardioprotection

G Heusch - Basic Research in Cardiology, 2019 - Springer
Cardioprotection aims at infarct size reduction and improvement of clinical outcome from
myocardial infarction. The translation of cardioprotection from preclinical and promising …

[HTML][HTML] Brain microvascular pericytes in vascular cognitive impairment and dementia

MT Uemura, T Maki, M Ihara, VMY Lee… - Frontiers in aging …, 2020 - frontiersin.org
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the
perivascular space in microvessels. Originally discovered in 19th century, pericytes had …

[HTML][HTML] Targeting pericytes for therapeutic approaches to neurological disorders

J Cheng, N Korte, R Nortley, H Sethi, Y Tang… - Acta …, 2018 - Springer
Many central nervous system diseases currently lack effective treatment and are often
associated with defects in microvascular function, including a failure to match the energy …

[HTML][HTML] Mapping the cardiac vascular niche in heart failure

F Peisker, M Halder, J Nagai, S Ziegler… - Nature …, 2022 - nature.com
The cardiac vascular and perivascular niche are of major importance in homeostasis and
during disease, but we lack a complete understanding of its cellular heterogeneity and …

The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection

DJ Hausenloy, W Chilian, F Crea… - Cardiovascular …, 2019 - academic.oup.com
The coronary circulation is both culprit and victim of acute myocardial infarction. The rupture
of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary …

[HTML][HTML] Cardiac pericytes mediate the remodeling response to myocardial infarction

P Quijada, S Park, P Zhao, KSS Kolluri… - The Journal of …, 2023 - Am Soc Clin Investig
Despite the prevalence of pericytes in the microvasculature of the heart, their role during
ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse …

No-reflow phenomenon in the heart and brain

RA Kloner, KS King… - American Journal of …, 2018 - journals.physiology.org
The no-reflow phenomenon refers to the observation that when an organ is made ischemic
by occlusion of a large artery supplying it, restoration of patency in that artery does not …