At present, many patients who undergo reperfusion immediately after percutaneous
coronary intervention will undergo microvascular obstruction and reduction in myocardial …

The adult mammalian heart lacks regenerative capacity and heals through activation of an
inflammatory cascade that leads to the formation of a collagen-based scar. Although scar …

Pericytes, as the mural cells surrounding the microvasculature, play a critical role in the
regulation of microcirculation; however, how these cells respond to ischemic stroke remains …

Background Ischemia preconditioning (IPC) ameliorates coronary no-reflow induced by
ischemia/reperfusion (I/R) injury, and pericytes play an important role in microvascular …

Capillaries within the microcirculation are essential for oxygen delivery and nutrient/waste
exchange, among other critical functions. Microvascular bioengineering approaches have …

Background Coronary microvascular dysfunction (CMD) is a pathophysiological feature of
diabetic heart disease. However, whether sodium-glucose cotransporter 2 (SGLT2) …

Pericytes (PCs)—mural cells that envelop endothelial cells (ECs) of microvessels—regulate
tissue‐specific vasculature development as well as maturation and maintenance of …

Pericytes (PCs) are abundant yet remain the most enigmatic and ill-defined cell population
in the heart. Here, we investigated whether PCs can be reprogrammed to aid …

Aims: Microvascular alterations occurring after myocardial infarction (MI) may represent a
risk factor for multi-organ failure. Here we used in vivo photoacoustic (PA) imaging to track …

During the last decade, extensive efforts have been made to comprehend cardiac cell
genetic and functional diversity. Such knowledge allows for the definition of the cardiac …