[HTML][HTML] Bovine milk extracellular vesicles (EVs) modification elicits skeletal muscle growth in rats

HA Parry, CB Mobley, PW Mumford… - Frontiers in …, 2019 - frontiersin.org
The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod
performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty …

A time course for markers of protein synthesis and degradation with hindlimb unloading and the accompanying anabolic resistance to refeeding

PA Roberson, KL Shimkus, JE Welles… - Journal of Applied …, 2020 - journals.physiology.org
Skeletal muscle atrophy is associated with disease, aging, and disuse. Hindlimb unloading
(HU) in animals provides an experimental model to study muscle atrophy. A comprehensive …

[HTML][HTML] Glucose-induced activation of mTORC1 is associated with Hexokinase2 binding to sestrins in HEK293T cells

PA Roberson, GN Kincheloe, JE Welles, D Xu… - The Journal of …, 2023 - Elsevier
Abstract Background Sestrins (SESN1-3) act as proximal sensors in leucine-induced
activation of the protein kinase mechanistic target of rapamycin (mTOR) in complex 1 …

Synergist ablation-induced hypertrophy occurs more rapidly in the plantaris than soleus muscle in rats due to different molecular mechanisms

MD Roberts, CB Mobley, CG Vann… - American Journal …, 2020 - journals.physiology.org
We examined molecular mechanisms that were altered during rapid soleus (type I fiber-
dominant) and plantaris (type II fiber-dominant) hypertrophy in rats. Twelve Wistar rats (3.5 …

Effect of whey protein supplementation during resistance training sessions on body mass and muscular strength: a meta-analysis

M Li, F Liu - Food & function, 2019 - pubs.rsc.org
This study evaluates the effect of whey protein (WP) supplementation with resistance
training (RT) on body mass and muscular strength through randomized controlled trials …

Skeletal muscle LINE-1 ORF1 mRNA is higher in older humans but decreases with endurance exercise and is negatively associated with higher physical activity

PA Roberson, MA Romero… - Journal of Applied …, 2019 - journals.physiology.org
The long interspersed nuclear element-1 (L1) is a retrotransposon that constitutes 17% of
the human genome and is associated with various diseases and aging. Estimates suggest …

[HTML][HTML] Bioreactor development for skeletal muscle hypertrophy and atrophy by manipulating uniaxial cyclic strain: proof of concept

KY Kamal, MA Othman, JH Kim, JM Lawler - npj Microgravity, 2024 - nature.com
Skeletal muscles overcome terrestrial, gravitational loading by producing tensile forces that
produce movement through joint rotation. Conversely, the microgravity of spaceflight …

Cellular and morphological changes with EAA supplementation before and after total knee arthroplasty

JB Muyskens, DM Foote, NJ Bigot… - Journal of Applied …, 2019 - journals.physiology.org
The purpose of this study was to investigate the underlying cellular basis of muscle atrophy
(Placebo) and atrophy reduction (essential amino acid supplementation, EAAs) in total knee …

[HTML][HTML] Soy Food Consumption Is Inversely Associated with Handgrip Strength: Results from the TCLSIH Cohort Study

H Wu, J Quan, X Wang, Y Gu, S Zhang, G Meng… - Nutrients, 2023 - mdpi.com
Background: Soy foods contain high levels of soy protein or isoflavones, which can stimulate
muscle protein synthesis and increase antioxidant capacity, and thus ameliorate muscle …

[HTML][HTML] Nutritional regulation of muscle stem cells in exercise and disease: The role of protein and amino acid dietary supplementation

KM Beaudry, ER Binet, N Collao, M De Lisio - Frontiers in Physiology, 2022 - frontiersin.org
Human skeletal muscle is a remarkedly plastic tissue that has a high capacity to adapt in
response to various stimuli. These adaptations are due in part to the function of muscle …