Enzymes are widely used in industry due to their high efficiency and selectivity. However,
their low stability during certain industrial processes can result in a significant loss of …

This review highlights the recent advancements in the field of nanozymes and their
applications in the development of point-of-care biosensors. The use of nanozymes as …

Cancer, as one of the leading causes of death worldwide, drives the advancement of cutting-
edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as …

Therapeutic enzymes are valuable biopharmaceuticals in various biomedical applications.
They have been successfully applied for fibrinolysis, cancer treatment, enzyme replacement …

Metabolic dysregulation constitutes a pivotal feature of cancer progression. Enzymes with
multiple metal active sites play a major role in this process. Here we report the first metabolic …

Abstract L-Asparaginase (L-ASNase), a bacterial enzyme that degrades asparagine, has
been commonly used in combination with several chemical drugs to treat malignant …

Abstract The Escherichia coli enzyme EcAIII catalyzes the hydrolysis of L‐Asn to L‐Asp and
ammonia. Using a nature‐inspired mutagenesis approach, we designed and produced five …

High-production capacity, secretion efficiency, metabolic diversities, and capability to carry
out posttranslational modifications enables filamentous fungi to be widely exploited as cell …

Background Enzyme therapy based on differential metabolism of cancer cells has
demonstrated promising potential as a treatment strategy. Nevertheless, the therapeutic …

Over the past few years, there has been a surge in the industrial production of recombinant
enzymes from microorganisms due to their catalytic characteristics being highly efficient …