A comprehensive insight into the molecular and cellular mechanisms of action of resveratrol on complications of sepsis a systematic review

M Vajdi, P Sefidmooye Azar… - Phytotherapy …, 2023 - Wiley Online Library
Sepsis and septic shock are still one of the most important medical challenges. Sepsis is an
extreme and uncontrolled response of the innate immune system to invading pathogenesis …

[HTML][HTML] Apoptosis and (in) pain—potential clinical implications

H Ribeiro, AB Sarmento-Ribeiro, JP Andrade… - Biomedicines, 2022 - mdpi.com
The deregulation of apoptosis is involved in the development of several pathologies, and
recent evidence suggests that apoptosis may be involved in chronic pain, namely in …

[HTML][HTML] Alginate Oligosaccharide Alleviated Cisplatin-Induced Kidney Oxidative Stress via Lactobacillus Genus-FAHFAs-Nrf2 Axis in Mice

Y Zhang, S Qin, Y Song, J Yuan, S Hu… - Frontiers in …, 2022 - frontiersin.org
Alginate oligosaccharide is the depolymerized product of alginate, a natural extract of brown
algae, which is associated with beneficial health effects. Here, we aimed to investigate the …

The beneficial role of Nrf2 in the endothelial dysfunction of atherosclerosis

Z Huang, M Wu, L Zeng, D Wang - Cardiology Research and …, 2022 - Wiley Online Library
Cardiovascular disease (CVD) is a serious public health issue in China, accounting for more
than 40% of all mortality, and it is the leading cause of death worldwide. Atherosclerosis is …

[HTML][HTML] Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic …

HRH Elsayed, MR Rabei, MMA Elshaer… - Frontiers in …, 2023 - frontiersin.org
Introduction Diabetes is a global disease, commonly complicated by neuropathy. The spinal
cord reacts to diabetes by neuronal apoptosis, microglial activation, and astrocytosis, with a …

Signaling pathways triggering therapeutic hydrogels in promoting chronic wound healing

F Chen, P Wu, H Zhang, G Sun - Macromolecular Bioscience, 2024 - Wiley Online Library
In recent years, there has been a significant increase in the prevalence of chronic wounds,
such as pressure ulcers, diabetic foot ulcers, and venous ulcers of the lower extremities. The …

[HTML][HTML] The interaction between carbon monoxide and hydrogen sulfide during chronic joint pain in young female mice

G Batallé, X Bai, O Pol - Antioxidants, 2022 - mdpi.com
A relationship between carbon monoxide (CO) and hydrogen sulfide (H2S) has been
described in different pathological conditions, but their interaction in modulating joint pain …

Selenomethionine protected BMECs from inflammatory injury and oxidative damage induced by Klebsiella pneumoniae by inhibiting the NF-κB and activating the Nrf2 …

X Ma, S Xu, J Li, L Cui, J Dong, X Meng, G Zhu… - International …, 2022 - Elsevier
Klebsiella pneumoniae (K. pneumoniae) is one of the main environmental pathogens
causing bovine mastitis. The incidence of bovine mastitis caused by K. pneumoniae is …

[HTML][HTML] C-phycocyanin alleviated cisplatin-induced oxidative stress and inflammation via gut microbiota—metabolites axis in mice

Y Zhang, L Li, S Qin, J Yuan, X Xie, F Wang, S Hu… - Frontiers in …, 2022 - frontiersin.org
C-phycocyanin is a natural protein extracted from Spirulina platensis. We aim to investigate
the preventive effect of C-phycocyanin on cisplatin chemotherapy-induced oxidative …

[HTML][HTML] The impact of UFP-512 in mice with osteoarthritis pain: the role of hydrogen sulfide

G Batallé, X Bai, G Balboni, O Pol - Antioxidants, 2023 - mdpi.com
The pain-relieving properties of opioids in inflammatory and neuropathic pain are
heightened by hydrogen sulfide (H2S). However, whether allodynia and functional and/or …