Amorphous solid dispersions (ASDs) are being employed frequently to improve
bioavailability of poorly soluble molecules by enhancing the rate and extant of dissolution in …

The development of oral dosage forms for poorly water-soluble active pharmaceutical
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …

Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …

Poorly water-soluble drugs are a significant and ongoing issue for the pharmaceutical
industry. An overview of recent developments for the preparation of spray-dried delivery …

Spray drying is a versatile technology that has been applied widely in the chemical, food,
and, most recently, pharmaceutical industries. This review focuses on engineering advances …

The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates
much of the early drug development portfolio and poses a major challenge in …

In this Commentary, the authors expand on their earlier studies of the solid-state long-term
isothermal crystallization of amorphous API from the glassy state in amorphous solid …

Among many methods to mitigate the solubility limitations of drug compounds, amorphous
solid dispersion (ASD) is considered to be one of the most promising strategies to enhance …

For the solubility and bioavailability of poorly soluble active pharmaceutical ingredients
(APIs) to be improved, the transformation of crystalline APIs to the amorphous state has often …

Amorphous solid dispersions (ASD) are one of the most adopted technologies for improving
the solubility of novel molecules. Formulation of ASDs using solvent free methods such as …