Comprehensive review of cardiovascular toxicity of drugs and related agents

P Mladěnka, L Applová, J Patočka… - Medicinal research …, 2018 - Wiley Online Library
Cardiovascular diseases are a leading cause of morbidity and mortality in most developed
countries of the world. Pharmaceuticals, illicit drugs, and toxins can significantly contribute to …

Combined oral contraceptives in the treatment of polycystic ovary syndrome

J Vrbikova, D Cibula - Human reproduction update, 2005 - academic.oup.com
Combined oral contraceptives (COC) are the most often used treatment modality for
polycystic ovary syndrome (PCOS). Undisputedly, COC suppress androgen production, thus …

The effect of atorvastatin in patients with polycystic ovary syndrome: a randomized double-blind placebo-controlled study

T Sathyapalan, ES Kilpatrick… - The Journal of Clinical …, 2009 - academic.oup.com
Context: Polycystic ovary syndrome (PCOS) is associated with increased risk of
cardiovascular morbidity, whereas statins are proven to reduce cardiovascular mortality and …

The association between the combined oral contraceptive pill and insulin resistance, dysglycemia and dyslipidemia in women with polycystic ovary syndrome: a …

IJ Halperin, S Sujana Kumar, DF Stroup… - Human …, 2011 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common endocrine disorder
of young women. First-line treatment is often the oral contraceptive pill (OC), but evidence …

Polycystic ovary syndrome, oral contraceptives and metabolic issues: new perspectives and a unifying hypothesis

S Nader, E Diamanti-Kandarakis - Human Reproduction, 2007 - academic.oup.com
In the chronic treatment of polycystic ovary syndrome (PCOS), oral contraceptive pills
(OCPs) are commonly used to induce regular menses, protect the endometrium and …

[HTML][HTML] Treatment with combined oral contraceptives induces a rise in serum C‐reactive protein in the absence of a general inflammatory response

M van Rooijen, LO Hansson, J Frostegård… - Journal of Thrombosis …, 2006 - Elsevier
Background: The role of inflammation in the pathogenesis of cardiovascular disease is well
established. C‐reactive protein (CRP) is the strongest independent predictor of myocardial …

Pharmacodynamics of combined estrogen-progestin oral contraceptives: 1. Effects on metabolism

C Bastianelli, M Farris, E Rosato, I Brosens… - Expert review of …, 2017 - Taylor & Francis
Introduction: The risk-benefit profile of any pharmacologic agent must be evaluated against
risks connected with the events to be avoided. This is especially true in the case of hormonal …

The effect of a combination therapy with myo-inositol and a combined oral contraceptive pill versus a combined oral contraceptive pill alone on metabolic, endocrine …

M Minozzi, D Costantino, C Guaraldi… - Gynecological …, 2011 - Taylor & Francis
Aim. Compare the effects of a combined contraceptive pill (OCP) in combination with myo-
inositol (MI) on endocrine, metabolic, and clinical parameters in patients with polycystic …

Metabolic impact of combined hormonal contraceptives containing estradiol

G Grandi, A Napolitano, A Cagnacci - Expert Opinion on Drug …, 2016 - Taylor & Francis
Introduction: Is the replacement of ethinyl-estradiol (EE) with estradiol (E2) in combined
hormonal contraceptives (CHCs) associated with fewer metabolic effects, leading to a further …

Oral contraceptives modify DNA methylation and monocyte-derived macrophage function

I Campesi, M Sanna, A Zinellu, C Carru… - Biology of sex …, 2012 - Springer
Background Fertile women may be encouraged to use contraception during clinical trials to
avoid potential drug effects on fetuses. However, hormonal contraception interferes with …