Host cell death is an intrinsic immune defense mechanism in response to microbial infection.
However, bacterial pathogens use many strategies to manipulate the host cell death and …

Intracellular parasitism by bacterial pathogens is a complex, multi-factorial process that has
been exploited successfully by a wide variety of organisms. Members of the Order …

In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen and the
causative agent of blinding trachoma. Although Chlamydia is protected from humoral …

Chlamydia trachomatis is a leading cause of genital and ocular infections for which no
vaccine exists. Upon entry into host cells, C. trachomatis resides within a membrane-bound …

The acquisition of host-derived lipids is essential for the pathogenesis of the obligate
intracellular bacteria Chlamydia trachomatis. Current models of chlamydial lipid acquisition …

There are few documented reports of antibiotic resistance in Chlamydia and no examples of
natural and stable antibiotic resistance in strains collected from humans. While there are …

Interferon-inducible GTPases of the Immunity Related GTPase (IRG) and Guanylate Binding
Protein (GBP) families provide resistance to intracellular pathogenic microbes. IRGs and …

Many bacterial pathogens have evolved the ability to subvert and exploit host functions in
order to enter and replicate in eukaryotic cells. For example, bacteria have developed …

Chlamydiae are obligate intracellular bacteria that replicate within an inclusion that is
trafficked to the peri-Golgi region where it fuses with exocytic vesicles. The host and …