Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

The role of pazopanib on tumour angiogenesis and in the management of cancers: A review

DK Chellappan, J Chellian, ZY Ng, YJ Sim… - Biomedicine & …, 2017 - Elsevier
Pazopanib is a relatively new compound to be introduced into the chemotherapy field. It is
thought to have decent anti-angiogenic properties, which gives an additional hope for the …

A PKM2 signature in the failing heart

ML Rees, J Subramaniam, Y Li, DJ Hamilton… - Biochemical and …, 2015 - Elsevier
A salient feature of the failing heart is metabolic remodeling towards predominant glucose
metabolism and activation of the fetal gene program. Sunitinib is a multitargeted receptor …

Elastic properties of lithium disilicate versus feldspathic inlays: effect on the bonding by 3D finite element analysis

FZ Trindade, LF Valandro, N de Jager… - Journal of …, 2018 - Wiley Online Library
Purpose To determine the elastic properties of five ceramic systems with different
compositions (lithium disilicate vs. feldspathic ceramics) and processing methods and …

Incidence and risk of sorafenib‐induced hypertension: A systematic review and meta‐analysis

Y Li, S Li, Y Zhu, X Liang, H Meng… - The Journal of …, 2014 - Wiley Online Library
Hypertension is one of the major side effects of sorafenib, and reported incidences vary
substantially among clinical trials. A systematic review was conducted using M edline, P ub …

Hypertension as a prognostic factor in metastatic renal cell carcinoma treated with tyrosine kinase inhibitors: a systematic review and meta-analysis

Y Liu, L Zhou, Y Chen, B Liao, D Ye, K Wang, H Li - Bmc Urology, 2019 - Springer
Background Conflicting evidence exists regarding the effect of hypertension on the
prognosis of metastatic renal cell carcinoma (mRCC) patients treated with tyrosine kinase …

Sunitinib, hypertension, and heart failure: a model for kinase inhibitor-mediated cardiotoxicity

R Gupta, ML Maitland - Current hypertension reports, 2011 - Springer
Kinase inhibitors have emerged as an important new class of agents for the treatment of
diverse tumors. Sunitinib malate is a small-molecule, oral, multi-kinase inhibitor approved for …

Hipertensión arterial inducida por el tratamiento con antiangiogénicos en el paciente oncológico

EA Landrove-Escalona… - Universidad Médica …, 2021 - medigraphic.com
Introducción: la hipertensión arterial una enfermedad multifactorial; existe una alta gama de
estímulos que pueden desencadenarla, entre ellos, los medicamentos. Objetivo: describir …

Lung cancer as a cardiotoxic state: a review

D Pérez-Callejo, M Torrente, MA Brenes, B Núñez… - Medical Oncology, 2017 - Springer
As the overall survival of patients with lung cancer continues to increase, more cancer
survivors are faced with the risk of developing treatment-related cardiovascular toxicities …

Can targeted therapy be successful without metronomic scheduling?

N André, E Pasquier, B Kamen - Current topics in medicinal …, 2012 - ingentaconnect.com
In medical oncology, targeted therapy has emerged over the last decade, as the most
promising strategy to fight cancer. In addition, a more complete understanding of tumor …