Abstract Treatment of large bone defects represents a great challenge in orthopedic and
craniomaxillofacial surgery. Traditional strategies in bone tissue engineering have focused …

Bone is a dynamic tissue composed of cells, an extracellular matrix, and mineralized portion.
Osteoblasts are responsible for proper bone formation and remodeling, and function. These …

Parathyroid hormone acts through its receptor, PTHR1, expressed on osteoblasts, to control
bone remodeling. Metabolic flexibility for energy generation has been demonstrated in …

Nanoparticles of a particular, evolutionarily old inorganic polymer found across the
biological kingdoms have attracted increasing interest in recent years not only because of …

Abstract Bone morphogenetic protein 9 (BMP9) is an effective osteogenic factor and a
promising candidate for bone tissue engineering. The osteoblastic potential of BMP9 needs …

Previously, we and others reported a rapid and dramatic increase in brain prostanoids (PG),
including prostaglandins, prostacyclins, and thromboxanes, under ischemia that is …

Low energy availability (LEA) is prevalent in active individuals and negatively impacts bone
turnover in young females. High‐impact exercise can promote bone health in an energy …

Mef2c is a transcription factor that mediates key cellular behaviors that promote
endochondral ossification and bone formation. Previously, Mef2c has been shown to …

Background Linoleic acid (LNA), an essential polyunsaturated fatty acid (PUFA), plays a
crucial role in cellular functions. However, excessive intake of LNA, characteristic of Western …

Abstract Purpose of the Review In this review, we discuss the most recent scientific
advances on the reciprocal regulatory interactions between the skeletal and hematopoietic …