Malaria: mechanisms of erythrocytic infection and pathological correlates of severe disease
K Haldar, SC Murphy, DA Milner Jr… - Annu. Rev. Pathol …, 2007 - annualreviews.org
Malaria is an ancient disease that continues to cause enormous human morbidity and
mortality. The life cycle of the causative parasite involves multiple tissues in two distinct host …
mortality. The life cycle of the causative parasite involves multiple tissues in two distinct host …
[HTML][HTML] Sequestration and tissue accumulation of human malaria parasites: can we learn anything from rodent models of malaria?
The sequestration of Plasmodium falciparum–infected red blood cells (irbcs) in the
microvasculature of organs is associated with severe disease; correspondingly, the …
microvasculature of organs is associated with severe disease; correspondingly, the …
[HTML][HTML] Malaria and COVID-19: common and different findings
F Di Gennaro, C Marotta, P Locantore, D Pizzol… - Tropical medicine and …, 2020 - mdpi.com
Malaria and COVID-19 may have similar aspects and seem to have a strong potential for
mutual influence. They have already caused millions of deaths, and the regions where …
mutual influence. They have already caused millions of deaths, and the regions where …
Targeting malaria virulence and remodeling proteins to the host erythrocyte
To establish infection in the host, malaria parasites export remodeling and virulence proteins
into the erythrocyte. These proteins can traverse a series of membranes, including the …
into the erythrocyte. These proteins can traverse a series of membranes, including the …
A host-targeting signal in virulence proteins reveals a secretome in malarial infection
Malaria parasites secrete proteins across the vacuolar membrane into the erythrocyte,
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
inducing modifications linked to disease and parasite survival. We identified an 11–amino …
SURFIN is a polymorphic antigen expressed on Plasmodium falciparum merozoites and infected erythrocytes
G Winter, S Kawai, M Haeggström… - The Journal of …, 2005 - rupress.org
The surfaces of the infected erythrocyte (IE) and the merozoite, two developmental stages of
malaria parasites, expose antigenic determinants to the host immune system. We report on …
malaria parasites, expose antigenic determinants to the host immune system. We report on …
[HTML][HTML] A molecular link between malaria and Epstein–Barr virus reactivation
A Chêne, D Donati, AO Guerreiro-Cacais… - PLoS …, 2007 - journals.plos.org
Although malaria and Epstein–Barr (EBV) infection are recognized cofactors in the genesis
of endemic Burkitt lymphoma (BL), their relative contribution is not understood. BL, the most …
of endemic Burkitt lymphoma (BL), their relative contribution is not understood. BL, the most …
Evolution of human-chimpanzee differences in malaria susceptibility: Relationship to human genetic loss of N-glycolylneuraminic acid
Chimpanzees are the closest evolutionary cousins of humans, sharing> 99% identity in most
protein sequences. Plasmodium falciparum is the major worldwide cause of malaria …
protein sequences. Plasmodium falciparum is the major worldwide cause of malaria …
[HTML][HTML] The Plasmodium falciparum STEVOR Multigene Family Mediates Antigenic Variation of the Infected Erythrocyte
M Niang, X Yan Yam, PR Preiser - PLoS pathogens, 2009 - journals.plos.org
Modifications of the Plasmodium falciparum–infected red blood cell (iRBC) surface have
been linked to parasite-associated pathology. Such modifications enable the parasite to …
been linked to parasite-associated pathology. Such modifications enable the parasite to …
Sporadic childhood Burkitt lymphoma incidence in the United States during 1992–2005
SM Mbulaiteye, RJ Biggar, K Bhatia… - Pediatric blood & …, 2009 - Wiley Online Library
Background The risk factors and co‐factors for sporadic childhood BL are unknown. We
investigated demographic and age‐specific characteristics of childhood BL (0–14 years) in …
investigated demographic and age‐specific characteristics of childhood BL (0–14 years) in …