Inflammatory bowel disease in children and adolescents

MJ Rosen, A Dhawan, SA Saeed - JAMA pediatrics, 2015 - jamanetwork.com
The inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn disease, are
chronic inflammatory disorders of the gastrointestinal tract most often diagnosed in …

25 years of anti-TNF treatment for inflammatory bowel disease: lessons from the past and a look to the future

GR D'Haens, S van Deventer - Gut, 2021 - gut.bmj.com
Anti-tumour necrosis factor (TNF) antibodies have been widely used for approximately 25
years now. The first clinical observations in patients with refractory Crohn's disease rapidly …

The medical management of paediatric Crohn's disease: an ECCO-ESPGHAN guideline update

PF Van Rheenen, M Aloi, A Assa… - Journal of Crohn's …, 2021 - academic.oup.com
Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn's disease [CD]. Methods We …

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease

FM Ruemmele, G Veres, KL Kolho… - Journal of Crohn's …, 2014 - academic.oup.com
Children and adolescents with Crohn's disease (CD) present often with a more complicated
disease course compared to adult patients. In addition, the potential impact of CD on growth …

Japanese guidelines for the management and treatment of generalized pustular psoriasis: the new pathogenesis and treatment of GPP

H Fujita, T Terui, K Hayama, M Akiyama… - The Journal of …, 2018 - Wiley Online Library
Generalized pustular psoriasis (GPP) is a rare disease characterized by recurrent fever and
systemic flushing accompanied by extensive sterile pustules. The committee of the …

Infliximab is not associated with increased risk of malignancy or hemophagocytic lymphohistiocytosis in pediatric patients with inflammatory bowel disease

JS Hyams, MC Dubinsky, RN Baldassano, RB Colletti… - Gastroenterology, 2017 - Elsevier
Background and Aims Immunosuppressive therapy for inflammatory bowel disease (IBD) in
pediatric patients is thought to increase the risk of malignancy and lymphoproliferative …

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

TD Walters, MO Kim, LA Denson, AM Griffiths… - Gastroenterology, 2014 - Elsevier
Background & Aims Standard therapy for children newly diagnosed with Crohn's disease
(CD) includes early administration of immunomodulators after initial treatment with …

Dietary therapy with the Crohn's disease exclusion diet is a successful strategy for induction of remission in children and adults failing biological therapy

R Sigall Boneh, C Sarbagili Shabat… - Journal of Crohn's …, 2017 - academic.oup.com
Abstract Background Loss of response [LoR] to biologics in Crohn's disease [CD] is a
significant clinical problem. Dietary therapy as a treatment strategy in this setting has not …

Diagnosis and management of inflammatory bowel disease in children

SB Oliveira, IM Monteiro - Bmj, 2017 - bmj.com
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
lifelong conditions that often begin in childhood. The implications of IBD are of particular …

Role of biologics and biosimilars in inflammatory bowel disease: current trends and future perspectives

P Rawla, T Sunkara, JP Raj - Journal of inflammation research, 2018 - Taylor & Francis
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammatory disease of the
gastrointestinal system. The spectrum is of predominantly two types, namely, ulcerative …