High-density lipoprotein (HDL) plays a fundamental role in the Reverse Cholesterol
Transport pathway. Prior to maturation, nascent HDL exist as disk-shaped phospholipid …

Lipids are hydrophobic and amphiphilic molecules involved in diverse functions such as
membrane structure, energy metabolism, immunity, and signaling. However, altered intra …

Recently, extracellular vesicles (EVs), such as exosomes, have been proposed to play an
influential role in the cell-to-cell spread of neurodegenerative diseases, including the …

Along with the urbanization and industrialization of countries, the prevalence of chronic
diseases has increased. There is ample evidence that ambient pollution can play a major …

Background Aberrant concentration, structure and functionality of High Density Lipoprotein
(HDL) are associated with many prevalent diseases, including cardiovascular disease and …

High density lipoproteins (HDL) and apolipoprotein AI (apoA-I) must leave the circulation
and pass the endothelium to exert their atheroprotective actions in the arterial wall. We …

Publisher Summary Lipoproteins are the products of many different genes. The major
apolipoproteins share properties distinguishing them from most lipid-free and membrane …

Lipids are biomolecules that are only found in living beings. The way and degree of
interaction of these biomolecules with water determine important aspects in some biological …

We have used a new ApoA-I transgenic mouse model to identify by global gene expression
profiling, candidate genes that affect lipid and lipoprotein metabolism in response to …

The current state of knowledge about the role of high density lipoproteins (HDL) indicates
that their anti-atherogenic function is mainly related to the effectiveness of their actions …