Liver fibrosis is a substantial risk factor for the development and progression of liver cancer,
which includes hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma …

According to the WHO's recently released worldwide cancer data for 2020, liver cancer
ranks sixth in morbidity and third in mortality among all malignancies. Hepatocellular …

Dissecting and understanding the cancer ecosystem, especially that around the tumor
margins, which have strong implications for tumor cell infiltration and invasion, are essential …

Abstract Background & Aims Metastasis remains the major reason for high mortality of HCC
patients. This study was designed to investigate the role of E-twenty-six-specific sequence …

Liver cancer, primarily hepatocellular carcinoma (HCC), exhibits highly heterogeneous
histological and molecular aberrations across tumors and within individual tumor nodules …

Background & Aims Remodeling the tumor microenvironment is a critical strategy for treating
advanced hepatocellular carcinoma (HCC). Yet, how distinct cell populations in the …

Hepatocellular carcinoma (HCC) is a common malignancy often associated with high
angiogenesis and immune suppression in the tumor microenvironment (TME). Targeting of …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. To date, systemic treatment for patients with unresectable or advanced disease …

Obesity is a global epidemic and overwhelming evidence indicates that it is a risk factor for
numerous cancers, including hepatocellular carcinoma (HCC), the third leading cause of …

Hepatocellular carcinoma (HCC) has a complex and changeable tumor microenvironment.
Despite emerging evidence focusing on autophagy process within immune cells, the …