Myotonic dystrophies (DM) are the most common muscular dystrophies in adults, which can
affect other non-skeletal muscle organs such as the heart, brain and gastrointestinal system …

Myotonic dystrophy type 1 (DM1), the most common muscular dystrophy affecting adults and
children, is a multi-systemic disorder affecting skeletal, cardiac, and smooth muscles as well …

Increasing evidences indicate that in Myotonic Dystrophy type 1 (DM1 or Steinert disease),
an autosomal dominant multisystem disorder caused by a (CTG) n expansion in DMPK gene …

Myotonic dystrophy (DM) is caused by expansions of C (C) TG repeats in the non-coding
regions of the DMPK and CNBP genes, and DM patients often suffer from sudden cardiac …

Abstract Introduction/Aims Although the extent of muscle weakness and organ complications
has not been well studied in patients with late‐onset myotonic dystrophy type 1 (DM1), adult …

Myotonic Dystrophies (DM, Dystrophia Myotonia) are autosomal dominant inherited
myopathies with a high prevalence across different ethnic regions. Despite some …

Background Myotonic dystrophy (DM) is a rare, inherited disorder with multi-systemic effects
that impact the skeletal muscles, eyes, heart, skin and gastrointestinal, endocrine …

Background Low uptake of presymptomatic testing and medically assisted reproduction in
families impacted by neurogenetic diseases prompted us to investigate how reproductive …

Myotonic dystrophy is a hereditary disorder with systemic involvement. The Italian Neuro-
Cardiology Network-“Rete delle Neurocardiologie”(INCN-RNC) is a unique collaborative …

In myotonic dystrophy type 1 (DM1), deregulated alternative splicing of the muscle chloride
channel Clcn1 causes myotonia, a delayed relaxation of muscles due to repetitive action …