Metabolic syndrome: updates on pathophysiology and management in 2021

G Fahed, L Aoun, M Bou Zerdan, S Allam… - International journal of …, 2022 - mdpi.com
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023 - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

2020 International Society of Hypertension global hypertension practice guidelines

T Unger, C Borghi, F Charchar, NA Khan… - …, 2020 - Am Heart Assoc
In the Guidelines, differentiation between optimal and essential standards were not always
possible, and were made in sections where it was most practical and sensible. The …

Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity

R Ross, IJ Neeland, S Yamashita, I Shai… - Nature Reviews …, 2020 - nature.com
Despite decades of unequivocal evidence that waist circumference provides both
independent and additive information to BMI for predicting morbidity and risk of death, this …

Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

J Ren, NN Wu, S Wang, JR Sowers… - Physiological …, 2021 - journals.physiology.org
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures–2019 update: cosponsored …

JI Mechanick, C Apovian, S Brethauer… - Surgery for Obesity and …, 2020 - Elsevier
Objective The development of these updated clinical practice guidelines (CPG) was
commissioned by the American Association of Clinical Endocrinologists, The Obesity …

Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies

A Jayedi, S Soltani, SZ Motlagh, A Emadi, H Shahinfar… - Bmj, 2022 - bmj.com
Objective To present a comprehensive review of the association between measures of body
weight, waist, and fat, and different ratios of these measures, and the risk of type 2 diabetes …

Central fatness and risk of all cause mortality: systematic review and dose-response meta-analysis of 72 prospective cohort studies

A Jayedi, S Soltani, MS Zargar, TA Khan, S Shab-Bidar - Bmj, 2020 - bmj.com
Objective To quantify the association of indices of central obesity, including waist
circumference, hip circumference, thigh circumference, waist-to-hip ratio, waist-to-height …

The definition and prevalence of obesity and metabolic syndrome

A Engin - Obesity and lipotoxicity, 2017 - Springer
Increase in prevalence of obesity has become a worldwide major health problem in adults,
as well as among children and adolescents. Furthermore, total adiposity and truncal …

Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention

K Watanabe, T Wilmanski, C Diener, JC Earls… - Nature medicine, 2023 - nature.com
Multiomic profiling can reveal population heterogeneity for both health and disease states.
Obesity drives a myriad of metabolic perturbations and is a risk factor for multiple chronic …