The prevalence of metabolic diseases is growing worldwide. Accumulating evidence
suggests that solute carrier (SLC) transporters contribute to the etiology of various metabolic …

Chronic kidney disease (CKD) is determined by an interplay of monogenic, polygenic, and
environmental risks. Autosomal dominant polycystic kidney disease (ADPKD) and COL4A …

Precision public health is an emerging practice to more granularly predict and understand
public health risks and customize treatments for more specific and homogeneous …

Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases,
and its development involves multiple mechanisms. Gut microbiota has been reported to be …

Genome-wide association studies have identified hundreds of genetic variants associated
with blood pressure (BP), but sequence variation accounts for a small fraction of the …

Understanding the genetic architecture of host proteins interacting with SARS-CoV-2 or
mediating the maladaptive host response to COVID-19 can help to identify new or repurpose …

Healthcare transformation is the product of a shared vision between a broad range of
stakeholders to establish the future of care delivery and to develop new patient-centered …

Elevated blood pressure is a major risk factor for cardiovascular disease and has a
substantial genetic contribution. Genetic variation influencing blood pressure has the …

Genomic analysis of longevity offers the potential to illuminate the biology of human aging.
Here, using genome-wide association meta-analysis of 606,059 parents' survival, we …

Genome-wide association analysis advanced understanding of blood pressure (BP), a
major risk factor for vascular conditions such as coronary heart disease and stroke …