BACKGROUND In humans, inadequate trophoblast invasion into the decidua is associated
with the 'great obstetrical syndromes' which include pre-eclampsia, foetal growth restriction …

Breast cancer is the most frequent malignancy in females. Due to its major impact on
population, this disease represents a critical public health problem that requires further …

Breast cancer is a complex and heterogeneous disease. Gene expression profiling has
contributed significantly to our understanding of this heterogeneity at a molecular level …

Drug screening—ie, testing the effects of a number of drugs in multiple cell lines—is used for
drug discovery and development, and can also be performed to evaluate the heterogeneity …

Cancer is still one of the leading diseases and causes of death in the world. More than 200
types of cancers are currently known. Early diagnosis still is an important integral part of …

Circulating tumour cells (CTCs) are rare tumour cells found in the circulatory system of
certain cancer patients. The clinical and functional significance of CTCs is still under …

Cell lines are still a tool of choice for many fields of biomedical research, including oncology.
Although cancer is a very complex disease, many discoveries have been made using …

Animal models for examining human breast cancer (HBC) carcinogenesis have been
extensively studied and proposed. With the recent advent of immunotherapy, significant …

In this study, we perform a dynamical analysis of a generalized tumor model using the
Caputo fractional-order derivative. Tumor growth models are widely used in biomedical …

Biological experiments are most often performed with immortalized cell lines because they
are readily available and can be expanded without limitation. However, cell lines may differ …