As the ubiquitin–proteasome system (UPS) regulates almost every biological process, the
dysregulation or aberrant expression of the UPS components causes many pathological …

Epigenetics is the study of heritable molecular determinants that are independent of
phenotypic features. The epigenetic features include DNA methylation, histone …

Bladder cancer is one of the most lethal cancers in the world. Despite the continuous
development of medical technologies and therapeutic strategies, the overall survival rate of …

Bladder cancer (BC) is a heterogeneous disease, and pyrroline‑5‑carboxylate reductase 1
(PYCR1) can promote the proliferation and invasion of BC cells and accelerate BC …

With the rapidly increasing incidence of bladder cancer in China and worldwide, great efforts
have been made to understand the detailed mechanism of bladder cancer tumorigenesis …

Bladder cancer (BCa) is a common malignancy with uncertain molecular mechanism. 7-
dehydrocholesterol reductase (DHCR7), the enzyme of mammalian sterol biosynthesis …

This study aimed to investigate the role and regulatory mechanism of RNF126 in
nasopharyngeal carcinoma. Firstly, the expression and prognosis of RNF126 were analyzed …

Urological cancers are considered as life-threatening diseases around the world. Bladder
cancer is one of the most malignant urological tumors with high mortality and morbidity …

Bladder cancer is one of the common malignant urothelial tumors. Post-translational
modification (PTMs), including ubiquitination, acetylation, methylation, and phosphorylation …

The metastasis a major hallmark of tumors that its significant is not only related to the basic
research, but clinical investigations have revealed that majority of cancer deaths are due to …