[HTML][HTML] Classification of neuroendocrine neoplasms: lights and shadows

S La Rosa, S Uccella - Reviews in endocrine and metabolic disorders, 2021 - Springer
Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplastic proliferations
showing different morphological features, immunophenotype, molecular background …

Precision medicine in gastroenteropancreatic neuroendocrine neoplasms: Where are we in 2023?

N Fazio, A La Salvia - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Precision medicine describes a target-related approach to tailoring diagnosis and treatment
of the individual patient. While this personalized approach is revoluzionizing many areas of …

[HTML][HTML] An organoid biobank of neuroendocrine neoplasms enables genotype-phenotype mapping

K Kawasaki, K Toshimitsu, M Matano, M Fujita, M Fujii… - Cell, 2020 - cell.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasm (NEN) that consists of
neuroendocrine tumor and neuroendocrine carcinoma (NEC) is a lethal but under …

[HTML][HTML] Enhancing the anti-tumour activity of 177Lu-DOTA-octreotate radionuclide therapy in somatostatin receptor-2 expressing tumour models by targeting PARP

C Cullinane, K Waldeck, L Kirby, BE Rogers, P Eu… - Scientific reports, 2020 - nature.com
Peptide receptor radionuclide therapy (PRRT) is an important treatment option for patients
with somatostatin receptor-2 (SSTR2)-expressing neuroendocrine tumour (NET) though …

[HTML][HTML] Gastrinoma

RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

[HTML][HTML] An overview of circulating biomarkers in neuroendocrine neoplasms: a clinical guide

M Bevere, F Masetto, ME Carazzolo, A Bettega… - Diagnostics, 2023 - mdpi.com
Neuroendocrine neoplasms (NENs) are a heterogeneous group of diseases that are
characterized by different behavior and clinical manifestations. The diagnosis and …

[HTML][HTML] Biomarkers for pancreatic neuroendocrine neoplasms (PanNENs) management—an updated review

M Bocchini, F Nicolini, S Severi, A Bongiovanni… - Frontiers in …, 2020 - frontiersin.org
Pancreatic neuroendocrine tumors (PanNENs) are rare sporadic cancers or develop as part
of hereditary syndromes. PanNENs can be both functioning and non-functioning based on …

Looking into digestive mixed neuroendocrine–nonneuroendocrine neoplasms: subtypes, prognosis, and predictive factors

S Uccella, S La Rosa - Histopathology, 2020 - Wiley Online Library
Mixed neuroendocrine–nonneuroendocrine neoplasms (MiNENs) of the digestive system
represent a challenge for both pathologists and clinicians. Their nomenclature has changed …

Neuroendocrine tumors: a relevant clinical update

EN Rizen, AT Phan - Current Oncology Reports, 2022 - Springer
Abstract Purpose of Review The field of neuroendocrine oncology has changed much since
the time of Oberndorfer first described and coined the term carcinoid. The purpose of this …

Head‐to‐head comparison between 18F‐DOPA PET/CT and 68Ga‐DOTA peptides PET/CT in detecting intestinal neuroendocrine tumours: A systematic review and …

A Piccardo, F Fiz, G Bottoni, M Ugolini… - Clinical …, 2021 - Wiley Online Library
Purpose The imaging of intestinal neuroendocrine tumours (NETs) relies on functional
positron emission tomography (PET) tracers; these tumours can be studied by means of both …