[HTML][HTML] Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics

EAH Keppler, CL Jenkins, TJ Davis, HD Bean - TrAC Trends in Analytical …, 2018 - Elsevier
Due to excellent separation capacity for complex mixtures of chemicals, comprehensive two-
dimensional gas chromatography (GC× GC) is being utilized with increasing frequency for …

Metabolomics and fish nutrition: a review in the context of sustainable feed development

S Roques, C Deborde, N Richard… - Reviews in …, 2020 - Wiley Online Library
Aquaculture is facing a strategic challenge to improve feed suitability and support the global
increase in fish production. Improvements in diet formulation for sustainable nutritional …

Comprehensive two-dimensional gas chromatography in environmental analysis

AM Muscalu, T Górecki - TrAC Trends in Analytical Chemistry, 2018 - Elsevier
Comprehensive two-dimensional gas chromatography (GC× GC) offers increased peak
capacity and selectivity relative to conventional one dimensional separations. The analysis …

[HTML][HTML] Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model

KA Overmyer, C Thonusin, NR Qi, CF Burant… - PloS one, 2015 - journals.plos.org
A critical application of metabolomics is the evaluation of tissues, which are often the primary
sites of metabolic dysregulation in disease. Laboratory rodents have been widely used for …

Analytical protocols based on LC–MS, GC–MS and CE–MS for nontargeted metabolomics of biological tissues

S Naz, DC Moreira dos Santos, A García, C Barbas - Bioanalysis, 2014 - Taylor & Francis
Invasive, site-specific metabolite information could be better obtained from tissues. Hence,
highly sensitive mass spectrometry-based metabolomics coupled with separation …

[HTML][HTML] Toxicometabolomics: small molecules to answer big toxicological questions

AM Araújo, F Carvalho, P Guedes de Pinho… - Metabolites, 2021 - mdpi.com
Given the high biological impact of classical and emerging toxicants, a sensitive and
comprehensive assessment of the hazards and risks of these substances to organisms is …

[HTML][HTML] High-throughput extraction and quantification method for targeted metabolomics in murine tissues

S Zukunft, C Prehn, C Röhring, G Möller… - Metabolomics, 2018 - Springer
Introduction Global metabolomics analyses using body fluids provide valuable results for the
understanding and prediction of diseases. However, the mechanism of a disease is often …

Preanalytical processing and biobanking procedures of biological samples for metabolomics research: A white paper, community perspective (for “Precision medicine …

JA Kirwan, L Brennan, D Broadhurst, O Fiehn… - Clinical …, 2018 - academic.oup.com
BACKGROUND The metabolome of any given biological system contains a diverse range of
low molecular weight molecules (metabolites), whose abundances can be affected by the …

Metabolomics: a high-throughput platform for metabolite profile exploration

J Cheng, W Lan, G Zheng, X Gao - Computational Systems Biology …, 2018 - Springer
Metabolomics aims to quantitatively measure small-molecule metabolites in biological
samples, such as bodily fluids (eg, urine, blood, and saliva), tissues, and breathe exhalation …

Evaluation of a single-stage consumable-free modulator for comprehensive two-dimensional gas chromatography: analysis of polychlorinated biphenyls …

AM Muscalu, M Edwards, T Górecki… - Journal of Chromatography …, 2015 - Elsevier
Comprehensive two-dimensional gas chromatography (GC× GC) has been rapidly growing
in popularity. The GC× GC separation is performed by interfacing a modulator between two …