Broadly neutralizing antibodies targeting HIV: Progress and challenges

N Paneerselvam, A Khan, BR Lawson - Clinical Immunology, 2023 - Elsevier
Anti-HIV broadly neutralizing antibodies (bNAbs) offer a novel approach to treating,
preventing, or curing HIV. Pre-clinical models and clinical trials involving the passive transfer …

An overview of human anti-HIV-1 neutralizing antibodies against diverse epitopes of HIV-1

S Kumar, S Singh, K Luthra - ACS omega, 2023 - ACS Publications
In this Review, we have addressed some recent developments in the discovery and
applications of anti-human immunodeficiency virus type− 1 (HIV− 1) broadly neutralizing …

Broadly neutralizing antibodies for HIV prevention: a comprehensive review and future perspectives

S Mahomed - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
The human immunodeficiency virus (HIV) epidemic remains a formidable global health
concern, with 39 million people living with the virus and 1.3 million new infections reported …

Engineering strategies of Anti-HIV antibody therapeutics in clinical development

N Pihlstrom, S Bournazos - Current Opinion in HIV and AIDS, 2023 - journals.lww.com
The development of Fc and Fab-engineered antibodies for the treatment of HIV continues to
show promising progress. These novel therapies have the potential to overcome the …