Merged magnetic resonance and light sheet microscopy of the whole mouse brain

GA Johnson, Y Tian, DG Ashbrook… - Proceedings of the …, 2023 - National Acad Sciences
We have developed workflows to align 3D magnetic resonance histology (MRH) of the
mouse brain with light sheet microscopy (LSM) and 3D delineations of the same specimen …

A resource for the detailed 3D mapping of white matter pathways in the marmoset brain

C Liu, FQ Ye, JD Newman, D Szczupak, X Tian… - Nature …, 2020 - nature.com
While the fundamental importance of the white matter in supporting neuronal communication
is well known, existing publications of primate brains do not feature a detailed description of …

Neurite orientation dispersion and density imaging of mouse brain microstructure

N Wang, J Zhang, G Cofer, Y Qi, RJ Anderson… - Brain Structure and …, 2019 - Springer
Advanced biophysical models like neurite orientation dispersion and density imaging
(NODDI) have been developed to estimate the microstructural complexity of voxels enriched …

Mapping the human subcortical auditory system using histology, postmortem MRI and in vivo MRI at 7T

KR Sitek, OF Gulban, E Calabrese, GA Johnson… - elife, 2019 - elifesciences.org
Studying the human subcortical auditory system non-invasively is challenging due to its
small, densely packed structures deep within the brain. Additionally, the elaborate three …

[PDF][PDF] Postnatal age-differential ASD-like transcriptomic, synaptic, and behavioral deficits in Myt1l-mutant mice

S Kim, H Oh, SH Choi, YE Yoo, YW Noh, Y Cho, GH Im… - Cell Reports, 2022 - cell.com
Myelin transcription factor 1 like (Myt1l), a zinc-finger transcription factor, promotes neuronal
differentiation and is implicated in autism spectrum disorder (ASD) and intellectual disability …

[HTML][HTML] Variability and heritability of mouse brain structure: Microscopic MRI atlases and connectomes for diverse strains

N Wang, RJ Anderson, DG Ashbrook… - Neuroimage, 2020 - Elsevier
Genome-wide association studies have demonstrated significant links between human brain
structure and common DNA variants. Similar studies with rodents have been challenging …

[HTML][HTML] Cytoarchitecture of the mouse brain by high resolution diffusion magnetic resonance imaging

N Wang, LE White, Y Qi, G Cofer, GA Johnson - Neuroimage, 2020 - Elsevier
MRI has been widely used to probe the neuroanatomy of the mouse brain, directly
correlating MRI findings to histology is still challenging due to the limited spatial resolution …

Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal …

SF Enam, SR Kader, N Bodkin, JG Lyon… - Journal of …, 2020 - Springer
Background Appropriately modulating inflammation after traumatic brain injury (TBI) may
prevent disabilities for the millions of those inflicted annually. In TBI, cellular mediators of …

Recent advances in highly accelerated 3D MRI

Y Zhou, H Wang, C Liu, B Liao, Y Li… - Physics in Medicine …, 2023 - iopscience.iop.org
Three-dimensional MRI has gained increasing popularity in various clinical applications due
to its improved through-plane spatial resolution, which enhances the detection of subtle …

[HTML][HTML] Resolution and b value dependent structural connectome in ex vivo mouse brain

S Crater, S Maharjan, Y Qi, Q Zhao, G Cofer, JC Cook… - Neuroimage, 2022 - Elsevier
Diffusion magnetic resonance imaging has been widely used in both clinical and preclinical
studies to characterize tissue microstructure and structural connectivity. The diffusion MRI …