Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer due to its highly
invasive nature that impedes the surgical removal of all tumor cells, making relapse …

In recent years, the functions of glial cells, namely, astrocytes and microglia, have gained
prominence in several diseases of the central nervous system, especially in glioblastoma …

Glioblastomas are incurable tumors infiltrating the brain. A subpopulation of glioblastoma
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …

The interactions between pairs of cells and within multicellular assemblies are critical to
many biological processes such as intercellular communication, tissue and organ formation …

Glutamate neurotoxicity has been implicated in stroke, head trauma, multiple sclerosis and
neurodegenerative diseases. Although recent data show that cultured glioma cells secrete …

Cells existing in the form of clusters often exhibit distinct physiological functions from their
monodispersed forms, which have a close association with tissue and organ development …

Cerebral plasticity, which is the dynamic potential of the brain to reorganize itself during
ontogeny, learning, or following damage, has been widely studied in the last decade, in …

Infiltration of the central nervous system by neoplastic cells in patients with glioblastoma
multiforme (GBM) leads to neurological dysfunction and eventually to death. The elucidation …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Cellular heterogeneity is a hallmark of advanced cancers and has been ascribed in part to a
population of self-renewing, therapeutically resistant cancer stem cells (CSCs) …