[HTML][HTML] Pharmacological properties of 4′, 5, 7-trihydroxyflavone (apigenin) and its impact on cell signaling pathways

R Abid, S Ghazanfar, A Farid, SM Sulaman, M Idrees… - Molecules, 2022 - mdpi.com
Plant bioactive compounds, particularly apigenin, have therapeutic potential and functional
activities that aid in the prevention of infectious diseases in many mammalian bodies and …

Apigenin in cancer therapy: From mechanism of action to nano-therapeutic agent

Y Zhou, Y Yu, H Lv, H Zhang, T Liang, G Zhou… - Food and Chemical …, 2022 - Elsevier
Apigenin (APG) is a flavonoid presence in beverages, vegetables, and fruits containing anti-
diabetic, anti-oxidant, and anti-viral activities, as well as cancer management properties …

Exploring the binding mechanism of pumpkin seed protein and apigenin: Spectroscopic analysis, molecular docking and molecular dynamics simulation

F Liang, Y Shi, J Shi, WW Cao - Food Hydrocolloids, 2023 - Elsevier
Apigenin is a vital flavonoid that has attracted considerable attention in recent years due to
its potent health benefits. Pumpkin seed protein (PSP) is a valuable by-product after …

[HTML][HTML] Multifaceted pharmacological potentials of curcumin, genistein, and tanshinone IIA through proteomic approaches: an in-depth review

FB Khan, P Singh, YF Jamous, SA Ali, Abdullah… - Cancers, 2022 - mdpi.com
Simple Summary Over the years, alternative and complementary medicine have garnered
much attention all across the globe. To this end, phytochemicals have intriguing potential …

Co-delivery of curcumin and quercetin in shellac nanocapsules for the synergistic antioxidant properties and cytotoxicity against colon cancer cells

S Jain, S Lenaghan, V Dia, Q Zhong - Food Chemistry, 2023 - Elsevier
Synergistic bioactivity of dietary polyphenols can enhance functional food development to
prevent chronic diseases like cancer. In this study, physicochemical properties and …

Hohenbuehelia serotina polysaccharides self-assembled nanoparticles for delivery of quercetin and their anti-proliferative activities during gastrointestinal digestion in …

X Li, P Zhou, Z Luo, R Feng, L Wang - International Journal of Biological …, 2022 - Elsevier
In this study, the self-assembled nanoparticles based on Hohenbuehelia serotina
polysaccharides (QC-HSP NPs) were fabricated to encapsulate quercetin for improving its …

[HTML][HTML] Apigenin, a natural flavonoid, promotes autophagy and ferroptosis in human endometrial carcinoma Ishikawa cells in vitro and in vivo

Y Liang, Q Zhong, R Ma, Z Ni, K Thakur, J Zhang… - Food Science and …, 2023 - Elsevier
Apigenin, a natural flavonoid has been reported against a variety of cancer types. However,
it is unclear whether apigenin can promote autophagy and ferroptosis in Ishikawa cells …

Enhancing the bioavailability of encapsulated hydrophobic nutraceuticals: Insights from in vitro, in vivo, and clinical studies

Y Abuhassira-Cohen, YD Livney - Current Opinion in Food Science, 2022 - Elsevier
Highlights•Attributes of the delivery system and food matrix affect the bioavailability.•These
are mainly particle size, vehicle composition, crystallinity and food matrix.•A good delivery …

Synthesis of Glutathione-Responsive Cyclomatrix Polyphosphazene for Multimodal Theranostic Nanodrug Delivery

J Li, R Liu, B Zhang, F Bai, L Zhao… - ACS Applied Polymer …, 2023 - ACS Publications
In this work, a multimodal (chemotherapeutic/photodynamic/photothermal) theranostic
nanodrug delivery platform was developed based on the synergetic action of self-framed …

Construction of cyclodextrin-based organic frameworks with adjustable size: Enhanced the physicochemical stability and controlled release characteristics of apigenin

M Yin, M Chen, BS Chiou, F Liu - Food Bioscience, 2023 - Elsevier
The poor physicochemical stability and bioavailability of apigenin were main factors that
limited its application in the food industry. The γ-cyclodextrin-metal-organic frameworks (γ …