Cognitive enhancing effect of rTMS combined with tDCS in patients with major depressive disorder: a double-blind, randomized, sham-controlled study

X Li, J Liu, S Wei, C Yu, D Wang, Y Li, J Li, W Zhuang… - BMC Medicine, 2024 - Springer
Background Cognitive dysfunction is one of the common symptoms in patients with major
depressive disorder (MDD). Repetitive transcranial magnetic stimulation (rTMS) and …

Monoamine involvement in the antidepressant-like effect of β-caryophyllene

DR de Oliveira, DM da Silva… - CNS & Neurological …, 2018 - ingentaconnect.com
Background: Major depressive disorder is a psychiatric disorder that affects 4.4% of the
population worldwide. Although the majority of antidepressant drugs ameliorate depressive …

Selective serotonin reuptake inhibitors and serotonin and noradrenaline reuptake inhibitors improve cognitive function in partial responders depressed patients …

S Castellano, A Ventimiglia, S Salomone… - CNS & Neurological …, 2016 - ingentaconnect.com
Background: Major Depressive disorder (MDD) is often accompanied by cognitive deficits,
involving attention, learning, memory and executive functioning. Selective Serotonin …

Vortioxetine administration attenuates cognitive and synaptic deficits in 5× FAD mice

LX Jiang, GD Huang, F Su, H Wang, C Zhang… - Psychopharmacology, 2020 - Springer
Rationale and objective Vortioxetine has been reported to exhibit a variety of
neurobiological functions and neuroprotective effects. In the present study, we aimed to …

Determination of vortioxetine in human serum and saliva samples by HPLC–DAD and HPLC–MS

K Wróblewski, A Petruczynik, B Buszewski… - Acta …, 2017 - akjournals.com
Vortioxetine is a new drug against major depressive disorder with high affinity for a range of
different serotonergic targets in the central nervous system. Therapeutic drug monitoring is …

Effectiveness, tolerability, and dropout rates of vortioxetine in comorbid depression: a naturalistic study

V De Carlo, M Vismara, B Grancini… - Human …, 2020 - Wiley Online Library
Objective Vortioxetine is a novel antidepressant whose safety, tolerability, and therapeutic
action have been supported by several studies. The present naturalistic study aimed to …

Effect of a 5-HT7 receptor antagonist on reversal learning in the rat attentional set-shifting test

A Hrnjadovic, J Friedmann, S Barhebreus… - ACS chemical …, 2020 - ACS Publications
5-HT7 receptor antagonism has been shown to ameliorate ketamine-induced schizophrenia-
like deficits in extradimensional set-shifting using the attentional set-shifting task (ASST) …

Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 …

SC Leiser, D Iglesias-Bregna… - Journal of …, 2015 - journals.sagepub.com
Antidepressants often disrupt sleep. Vortioxetine, a multimodal antidepressant acting
through serotonin (5-HT) transporter (SERT) inhibition, 5-HT3, 5-HT7 and 5-HT1D receptor …

The influence of ketamine's repeated treatment on brain topology does not suggest an antidepressant efficacy

N Gass, R Becker, J Reinwald, A Cosa-Linan… - Translational …, 2020 - nature.com
As ketamine is increasingly used as an effective antidepressant with rapid action, sustaining
its short-lived efficacy over a longer period of time using a schedule of repeated injections …

Behavioral and Biochemical Effects of Mukia madrespatana Following Single Immobilization Stress on Rats

N Samad, A Ali, F Yasmin, R Ullah, A Bari - Medicina, 2020 - mdpi.com
Background and Objectives: Elevated oxidative stress has been shown to play an important
role in the diagnosis and prognosis of stress and memory-related complications. Mukia …