Developing therapeutics for Alzheimer's disease: progress and challenges
MS Wolfe - 2016 - books.google.com
Developing Therapeutics for Alzheimer's Disease: Progress and Challenges provides a
thorough overview of the latest advances toward the development of therapeutics for …
thorough overview of the latest advances toward the development of therapeutics for …
Depressive symptoms are associated with low serotonin levels in plasma but are not 5–HTTLPR genotype dependent in older adults
PE Trujillo-Hernández, A Sáenz-Galindo… - The Spanish Journal …, 2021 - cambridge.org
Depressive symptoms are diagnosed by physicians using scales but their pathophysiology
is unclear. Low serotonin (5–HT) levels play an important role in depression, and the 5–HT …
is unclear. Low serotonin (5–HT) levels play an important role in depression, and the 5–HT …
[PDF][PDF] Опыт применения вальдоксана при депрессиях, протекающих с когнитивными нарушениями
ВЭ Медведев, АЮ Тер-Исраелян… - … и психиатрии им …, 2018 - researchgate.net
Цель исследования. Оценка эффективности и переносимости монотерапии
вальдоксаном (агомелатин) у больных депрессией с выраженными когнитивными …
вальдоксаном (агомелатин) у больных депрессией с выраженными когнитивными …
Translational neurophysiological markers for activity of the metabotropic glutamate receptor (mGluR2) modulator JNJ-40411813: Sleep EEG correlates in rodents and …
A Ahnaou, P De Boer, H Lavreysen, H Huysmans… - …, 2016 - Elsevier
Alterations in rapid eye movement sleep (REM) have been suggested as valid translational
efficacy markers: activation of the metabotropic glutamate receptor 2 (mGluR2) was shown …
efficacy markers: activation of the metabotropic glutamate receptor 2 (mGluR2) was shown …
Role of cyclooxygenase inhibitors in diminution of dissimilar stress-induced depressive behavior and memory impairment in rats
Memory functions can be considerably affected by various life events and stress has shown
to be a chief regulator. Different stress patterns have distinct effects on the overall …
to be a chief regulator. Different stress patterns have distinct effects on the overall …
[PDF][PDF] Prescriber's guide to using 3 new antidepressants
A Elmaadawi, N Singh, J Reddy, SJ Nasr - Curr Psychiatry, 2016 - cdn.mdedge.com
Vilazodone also has a moderate effect on the 5-HT4 receptor and on dopamine and
norepinephrine uptake inhibition. The unique presynaptic 5-HT1A partial agonism of …
norepinephrine uptake inhibition. The unique presynaptic 5-HT1A partial agonism of …
Depression severity and concentration difficulties are independently associated with HRQOL in patients with unipolar depressive disorders
A Fattori, L Neri, A Bellomo, M Vaggi, C Mencacci… - Quality of Life …, 2017 - Springer
Purpose Cognitive impairment is a core feature of major depressive disorder (MDD), and
dysfunctions in this area strongly contribute to MDD-associated disability. Whether cognitive …
dysfunctions in this area strongly contribute to MDD-associated disability. Whether cognitive …
死亡相关蛋白激酶1 与重度抑郁认知障碍有关
XH Li, HC Zhu, XM Cui, W Wang, L Yang… - 中国神经再生研究 …, 2023 - sjzsyj.com.cn
作者既往研究发现, 重度抑郁小鼠模型海马组织中死亡相关蛋白激酶1 表达增加,
而死亡相关蛋白激酶1 与阿尔茨海默症认知功能障碍有关, 且抑郁是阿尔茨海默症的高危诱发 …
而死亡相关蛋白激酶1 与阿尔茨海默症认知功能障碍有关, 且抑郁是阿尔茨海默症的高危诱发 …
Crystal structures, X-ray photoelectron spectroscopy, thermodynamic stabilities, and improved solubilities of 2-hydrochloride salts of vortioxetine
J Li, LY Li, SF He, S Li, CZ Dong, L Zhang - Journal of Pharmaceutical …, 2017 - Elsevier
Two vortioxetine (VOT) salts with hydrochloride (VOT-HCl and VOT-0.5 HCl) were prepared
and structurally characterized. VOT-HCl features 1-dimensional P/M helical chains through …
and structurally characterized. VOT-HCl features 1-dimensional P/M helical chains through …
Effects on EEG of drugs and toxic substances
M Brienza, P Pulitano, O Mecarelli - Clinical electroencephalography, 2019 - Springer
The use of different drugs in clinical practice has enhanced the importance of pharmaco-
EEG (P-EEG) studies in recent years. The first part of this chapter will discuss the general …
EEG (P-EEG) studies in recent years. The first part of this chapter will discuss the general …