Using electronic health records for clinical pharmacology research: Challenges and considerations

E Jafari, MH Blackman, JH Karnes… - Clinical and …, 2024 - Wiley Online Library
Electronic health records (EHRs) contain a vast array of phenotypic data on large numbers
of individuals, often collected over decades. Due to the wealth of information, EHR data …

A general framework for developing computable clinical phenotype algorithms

DS Carrell, JS Floyd, S Gruber… - Journal of the …, 2024 - academic.oup.com
Objective Present a general framework providing high-level guidance to developers of
computable algorithms for identifying patients with specific clinical conditions (phenotypes) …

Demographics, Trends, and Clinical Characteristics of HIV Pre-Exposure Prophylaxis Recipients and People Newly Diagnosed with HIV from Large Electronic Health …

Y Liu, KA Siddiqi, H Cho, H Park… - AIDS Patient Care and …, 2024 - liebertpub.com
Florida is one of the HIV epicenters with high incidence and marked sociodemographic
disparities. We analyzed a decade of statewide electronic health record/claims data …

Develop and validate a computable phenotype for the identification of Alzheimer's disease patients using electronic health record data

X He, R Wei, Y Huang, Z Chen, T Lyu… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Alzheimer's disease (AD) is often misclassified in electronic health records
(EHRs) when relying solely on diagnosis codes. This study aimed to develop a more …

[HTML][HTML] Validation of human immunodeficiency virus diagnosis codes among women enrollees of a US health plan

G Pocobelli, M Oliver, L Albertson-Junkans… - BMC Health Services …, 2024 - Springer
Background Efficiently identifying patients with human immunodeficiency virus (HIV) using
administrative health care data (eg, claims) can facilitate research on their quality of care …

The impact of electronic health records (EHR) data continuity on prediction model fairness and racial-ethnic disparities

Y Huang, J Guo, Z Chen, J Xu, WT Donahoo… - arXiv preprint arXiv …, 2023 - arxiv.org
Electronic health records (EHR) data have considerable variability in data completeness
across sites and patients. Lack of" EHR data-continuity" or" EHR data-discontinuity", defined …

Developing a computable phenotype for glioblastoma

S Yan, K Melnick, X He, T Lyu, RSF Moor… - Neuro …, 2024 - academic.oup.com
Background Glioblastoma is the most common malignant brain tumor, and thus it is
important to be able to identify patients with this diagnosis for population studies. However …

[HTML][HTML] Automated HIV Case Identification from the MIMIC-IV Database

K Jiang, T Cao - AMIA Summits on Translational Science …, 2024 - ncbi.nlm.nih.gov
Automatic HIV phenotyping is needed for HIV research based on electronic health records
(EHRs). MIMIC-IV, an extension of MIMIC-III, contains more than 520,000 hospital …

Computational phenotyping with the All of Us Research Program: identifying underrepresented people with HIV or at risk of HIV

X Yang, J Zhang, R Cai, C Liang, B Olatosi… - JAMIA …, 2023 - academic.oup.com
Objective This study aims to identify the people living with HIV (PWH) and pre-exposure
prophylaxis (PrEP) users in the All of Us (AoU) database by integrating information from both …