Pain chronification: what should a non-pain medicine specialist know?

B Morlion, F Coluzzi, D Aldington… - … medical research and …, 2018 - Taylor & Francis
Objective: Pain is one of the most common reasons for an individual to consult their primary
care physician, with most chronic pain being treated in the primary care setting. However …

Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models

J Vollert, W Magerl, R Baron, A Binder… - Pain, 2018 - journals.lww.com
As an indirect approach to relate previously identified sensory phenotypes of patients
suffering from peripheral neuropathic pain to underlying mechanisms, we used a published …

The current view on the paradox of pain in autism spectrum disorders

OV Bogdanova, VB Bogdanov, A Pizano… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder, which affects 1 in 44
children and may cause severe disabilities. Besides socio-communicational difficulties and …

Comparison of five conditioned pain modulation paradigms and influencing personal factors in healthy adults

MG Mertens, L Hermans, G Crombez… - … Journal of Pain, 2021 - Wiley Online Library
Background Conditioned pain modulation (CPM) methods are experimental procedures to
assess presumed descending nociceptive modulatory pathways. Various CPM‐methods are …

The type of sport matters: Pain perception of endurance athletes versus strength athletes

T Assa, N Geva, Y Zarkh, R Defrin - European Journal of Pain, 2019 - Wiley Online Library
Background Studies assessing athletes' pain sensitivity yield inconsistent data, which
demonstrate either increased pain threshold and tolerance in athletes than controls or …

[HTML][HTML] A randomized, sham-controlled trial of repetitive transcranial magnetic stimulation targeting M1 and S2 in central poststroke pain: a pilot trial

J Ojala, J Vanhanen, H Harno, P Lioumis… - … : Technology at the …, 2022 - Elsevier
Objectives Central poststroke pain (CPSP), a neuropathic pain condition, is difficult to treat.
Repetitive transcranial magnetic stimulation (rTMS) targeted to the primary motor cortex (M1) …

Diffuse noxious inhibitory controls and conditioned pain modulation: a shared neurobiology within the descending pain inhibitory system?

L Sirucek, RP Ganley, HU Zeilhofer, P Schweinhardt - Pain, 2023 - journals.lww.com
Descending pain inhibition is a key component of physiological and pathological pain
processing. 70 Various neurotransmitter systems underlie different descending pain …

Within-session test-retest reliability of pressure pain threshold and mechanical temporal summation in healthy subjects

C Mailloux, LD Beaulieu, TH Wideman… - PLoS …, 2021 - journals.plos.org
Objective To determine the absolute and relative intra-rater within-session test-retest
reliability of pressure pain threshold (PPT) and mechanical temporal summation of pain …

Discovery of endogenous opioid systems: what it has meant for the clinician's understanding of pain and its treatment

JC Ballantyne, MD Sullivan - Pain, 2017 - journals.lww.com
Before the discovery of the endogenous opioid system in the 1970s, opioids were
understood only through the lens of opioid drug effects. Opium produced sleep, pain relief …

[HTML][HTML] Motor cortex transcranial direct current stimulation effects on knee osteoarthritis pain in elderly subjects with dysfunctional descending pain inhibitory system …

DRB Tavares, JEF Okazaki, MV de Andrade Santana… - Brain stimulation, 2021 - Elsevier
Background Although evidence has indicated a positive effect of transcranial direct current
stimulation (tDCS) on reducing pain, few studies have focused on the elderly population with …