The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given
people a novel understanding of the neuroendocrine regulation in human reproduction …

Endometriosis and polycystic ovary syndrome (PCOS) are two common female reproductive
disorders with a significant impact on the health and quality of life of women affected. A …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women and a
major cause of anovulatory infertility. A diagnosis of PCOS is established based the …

Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …

Background Kisspeptin is the leading upstream regulator of pulsatile and surge
Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as …

BACKGROUND According to the Developmental Origins of Health and Disease (DOHaD)
hypothesis, environmental changes taking place during early maturational periods may alter …

Cadmium (Cd), a toxic heavy metal, is a known endocrine disruptor that is associated with
reproductive complications. However, few studies have explored the effects of Cd exposure …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age and is the leading cause of anovulatory subfertility. Increased …

Polycystic ovarian syndrome (PCOS), the most common endocrinopathy affecting women
worldwide, is characterized by elevated luteinizing hormone (LH) pulse frequency due to the …