Breast milk, a source of beneficial microbes and associated benefits for infant health

KE Lyons, CA Ryan, EM Dempsey, RP Ross, C Stanton - Nutrients, 2020 - mdpi.com
Human breast milk is considered the optimum feeding regime for newborn infants due to its
ability to provide complete nutrition and many bioactive health factors. Breast feeding is …

[HTML][HTML] Invited review: Milk lactose—Current status and future challenges in dairy cattle

A Costa, N Lopez-Villalobos, NW Sneddon… - Journal of dairy …, 2019 - Elsevier
Lactose is the main carbohydrate in mammals' milk, and it is responsible for the osmotic
equilibrium between blood and alveolar lumen in the mammary gland. It is the major bovine …

Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation

JS Osorio, J Lohakare, M Bionaz - Physiological genomics, 2016 - journals.physiology.org
The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

Targeting glucose transporters for breast cancer therapy: the effect of natural and synthetic compounds

AM Barbosa, F Martel - Cancers, 2020 - mdpi.com
Reprogramming of cellular energy metabolism is widely accepted to be a cancer hallmark.
The deviant energetic metabolism of cancer cells-known as the Warburg effect-consists in …

Physiology of milk secretion

S Truchet, E Honvo-Houéto - … Practice & Research Clinical Endocrinology & …, 2017 - Elsevier
Milk is a unique and complete nutritive source for the mammal neonate, also providing
immune protection and developmental signals. Lactation is a complex process, proper to the …

Glucose metabolism and dynamics of facilitative glucose transporters (GLUTs) under the influence of heat stress in dairy cattle

Z Abbas, A Sammad, L Hu, H Fang, Q Xu, Y Wang - Metabolites, 2020 - mdpi.com
Heat stress is one of the main threats to dairy cow production; in order to resist heat stress,
the animal exhibits a variety of physiological and hormonal responses driven by complex …

Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations

JM Ayuso, A Gillette, K Lugo-Cintrón… - …, 2018 - thelancet.com
Background Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During
DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment …

PSMA-targeted nanoparticles for specific penetration of blood-brain tumor barrier and combined therapy of brain metastases

J Ni, T Miao, M Su, NU Khan, X Ju, H Chen… - Journal of Controlled …, 2021 - Elsevier
Breast cancer brain metastases (BCBM) represent a major cause of morbidity and mortality
among patients with breast cancer. Systemic drug therapy, which is usually effective against …

Culture Models to investigate mechanisms of milk production and blood-milk barrier in mammary epithelial cells: a review and a protocol

K Kobayashi - Journal of Mammary Gland Biology and Neoplasia, 2023 - Springer
Mammary epithelial cells (MECs) are the only cell type that produces milk during lactation.
MECs also form less-permeable tight junctions (TJs) to prevent the leakage of milk and …

[HTML][HTML] Symposium review: The impact of absorbed nutrients on energy partitioning throughout lactation

P Piantoni, MJ VandeHaar - Journal of Dairy Science, 2023 - Elsevier
Most nutrition models and some nutritionists view ration formulation as accounting
transactions to match nutrient supplies with nutrient requirements. However, diet and stage …