Biomolecular electrostatics and solvation: a computational perspective
An understanding of molecular interactions is essential for insight into biological systems at
the molecular scale. Among the various components of molecular interactions, electrostatics …
the molecular scale. Among the various components of molecular interactions, electrostatics …
Slowing and controlling the translocation of DNA in a solid-state nanopore
DNA sequencing methods based on nanopores could potentially represent a low-cost and
high-throughput pathway to practical genomics, by replacing current sequencing methods …
high-throughput pathway to practical genomics, by replacing current sequencing methods …
Slowing down DNA translocation through a nanopore in lithium chloride
SW Kowalczyk, DB Wells, A Aksimentiev, C Dekker - Nano letters, 2012 - ACS Publications
The charge of a DNA molecule is a crucial parameter in many DNA detection and
manipulation schemes such as gel electrophoresis and lab-on-a-chip applications. Here, we …
manipulation schemes such as gel electrophoresis and lab-on-a-chip applications. Here, we …
DNA sequencing: an overview of solid-state and biological nanopore-based methods
MM Mohammadi, O Bavi - Biophysical reviews, 2022 - Springer
The field of sequencing is a topic of significant interest since its emergence and has become
increasingly important over time. Impressive achievements have been obtained in this field …
increasingly important over time. Impressive achievements have been obtained in this field …
Controlling DNA translocation through solid-state nanopores
Z Yuan, Y Liu, M Dai, X Yi, C Wang - Nanoscale research letters, 2020 - Springer
Compared with the status of bio-nanopores, there are still several challenges that need to be
overcome before solid-state nanopores can be applied in commercial DNA sequencing …
overcome before solid-state nanopores can be applied in commercial DNA sequencing …
The structure and intermolecular forces of DNA condensates
J Yoo, A Aksimentiev - Nucleic acids research, 2016 - academic.oup.com
Spontaneous assembly of DNA molecules into compact structures is ubiquitous in biological
systems. Experiment has shown that polycations can turn electrostatic self-repulsion of DNA …
systems. Experiment has shown that polycations can turn electrostatic self-repulsion of DNA …
Designing a polycationic probe for simultaneous enrichment and detection of microRNAs in a nanopore
The nanopore sensor can detect cancer-derived nucleic acid biomarkers such as
microRNAs (miRNAs), providing a noninvasive tool potentially useful in medical diagnostics …
microRNAs (miRNAs), providing a noninvasive tool potentially useful in medical diagnostics …
Topological Jamming of Spontaneously Knotted Polyelectrolyte<? format?> Chains Driven Through a Nanopore
The advent of solid state nanodevices allows for interrogating the physicochemical
properties of a polyelectrolyte chain by electrophoretically driving it through a nanopore …
properties of a polyelectrolyte chain by electrophoretically driving it through a nanopore …
DNA–DNA interactions in tight supercoils are described by a small effective charge density
C Maffeo, R Schöpflin, H Brutzer, R Stehr… - Physical review …, 2010 - APS
DNA-DNA interactions are important for genome compaction and transcription regulation. In
studies of such complex processes, DNA is often modeled as a homogeneously charged …
studies of such complex processes, DNA is often modeled as a homogeneously charged …
Structure-guided DNA–DNA attraction mediated by divalent cations
A Srivastava, R Timsina, S Heo… - Nucleic acids …, 2020 - academic.oup.com
Probing the role of surface structure in electrostatic interactions, we report the first
observation of sequence-dependent dsDNA condensation by divalent alkaline earth metal …
observation of sequence-dependent dsDNA condensation by divalent alkaline earth metal …