[HTML][HTML] Gallium and its competing roles with iron in biological systems
CR Chitambar - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
Gallium, a group IIIa metal, shares chemical properties with iron. Studies have shown that
gallium-based compounds have potential therapeutic activity against certain cancers and …
gallium-based compounds have potential therapeutic activity against certain cancers and …
Mechanisms of therapeutic activity for gallium
LR Bernstein - Pharmacological reviews, 1998 - ASPET
Gallium, a semi-metallic element in group 13 (IIIa) of the periodic table, has shown efficacy
in the treatment of several apparently diverse disorders. These disorders can be broadly …
in the treatment of several apparently diverse disorders. These disorders can be broadly …
Metabolism and possible health effects of aluminum.
PO Ganrot - Environmental health perspectives, 1986 - ehp.niehs.nih.gov
Literature regarding the biochemistry of aluminum and eight similar ions is reviewed. Close
and hitherto unknown similarities were found. A hypothetical model is presented for the …
and hitherto unknown similarities were found. A hypothetical model is presented for the …
Promises and failures of gallium as an antibacterial agent
F Minandri, C Bonchi, E Frangipani, F Imperi… - Future …, 2014 - Taylor & Francis
Gallium has a long history as a diagnostic and chemotherapeutic agent. The
pharmacological properties of Ga (III) rely on chemical mimicry; when Ga (III) is exogenously …
pharmacological properties of Ga (III) rely on chemical mimicry; when Ga (III) is exogenously …
Gallium-containing anticancer compounds
CR Chitambar - Future medicinal chemistry, 2012 - Taylor & Francis
There is an ever pressing need to develop new drugs for the treatment of cancer. Gallium
nitrate, a group IIIa metal salt, inhibits the proliferation of tumor cells in vitro and in vivo and …
nitrate, a group IIIa metal salt, inhibits the proliferation of tumor cells in vitro and in vivo and …
The binding and transport of alternative metals by transferrin
JB Vincent, S Love - Biochimica et Biophysica Acta (BBA)-General …, 2012 - Elsevier
BACKGROUND: The iron transport protein of the blood plasma, transferrin, is maintained
only with about 30% of its capacity to bind Fe3+ ions; this leaves the protein the potential …
only with about 30% of its capacity to bind Fe3+ ions; this leaves the protein the potential …
[HTML][HTML] Effect of morphology and (Sn, Cr) doping on in vitro antiproliferation properties of hydrothermally synthesized 1D GaOOH nanostructures
GaOOH powders of submicron dimensions were synthesized through a simple, surfactant-
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …
Gallium radiopharmaceutical chemistry
MA Green, MJ Welch - International Journal of Radiation Applications and …, 1989 - Elsevier
There are two gallium radioisotopes, 67Ga and 68Ga, possessing nuclear properties”'that
make them attractive for use in nuclear medicine (Table 1). The first, 67Ga, is cyclotron …
make them attractive for use in nuclear medicine (Table 1). The first, 67Ga, is cyclotron …
The therapeutic potential of iron-targeting gallium compounds in human disease: From basic research to clinical application
CR Chitambar - Pharmacological research, 2017 - Elsevier
Gallium, group IIIa metal, shares certain chemical characteristics with iron which enable it to
function as an iron mimetic that can disrupt iron-dependent tumor cell growth. Gallium may …
function as an iron mimetic that can disrupt iron-dependent tumor cell growth. Gallium may …
Multivalent ions and biomolecules: Attempting a comprehensive perspective
O Matsarskaia, F Roosen‐Runge… - ChemPhysChem, 2020 - Wiley Online Library
Ions are ubiquitous in nature. They play a key role for many biological processes on the
molecular scale, from molecular interactions, to mechanical properties, to folding, to self …
molecular scale, from molecular interactions, to mechanical properties, to folding, to self …