Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Objective To prospectively evaluate safety and efficacy of brain-responsive neurostimulation
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …

It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by
infrequent seizures based on patient or caregiver reports and limited duration clinical …

Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …

Inaccurate subjective seizure counting poses treatment and diagnostic challenges and thus
suboptimal quality in epilepsy management. The limitations of existing hospital‐and home …

Abstract Machine learning (ML) is increasingly recognized as a useful tool in healthcare
applications, including epilepsy. One of the most important applications of ML in epilepsy is …

Epileptic seizures occur as a result of a process that develops over time and space in
epileptic networks. In this study, we aim at developing a generalizable method for patient …

Epilepsy is a unique neurologic condition characterized by recurrent seizures, where
causes, underlying biomarkers, triggers, and patterns differ across individuals. The …

Objective Seizure forecasting may provide patients with timely warnings to adapt their daily
activities and help clinicians deliver more objective, personalized treatments. Although …