The pharmacokinetics and androgenic activity of Estrostep®, a new oral contraceptive
providing low-dose estrogen in a graduated sequence with a constant dose of progestin …

The pharmacokinetics of gestodene (GEST) and ethinylestradiol (EE 2) were determined in
14 healthy women (age 18 to 32 years) during a treatment period of three months with a new …

Long-term heavy alcohol intake is associated with endocrinological abnormalities the
mechanisms of which are still unclear. The objective of the present study was to investigate …

Objective: To examine the influence of daily oral administration of ethinyloestradiol on the
total clearance of 13 C-labeled ethinyloestradiol in women. Methods: 19, healthy, young …

An acute elevation in estradiol during alcohol intake has been reported in postmenopausal
women on estrogen replacement therapy. The objective of the present study was to …

Tibolone is used for the treatment of climacteric symptoms in postmenopausal women. It is
metabolised in a tissue-specific manner so that while some metabolites exert estrogenic …

Le mauvais pronostic du cancer de l'ovaire est étroitement lié au stade au moment du
diagnostic et justifie de développer des stratégies de dépistage et de prévention efficaces …

Recent evidence indicates high-grade serous ovarian cancer originates from the fallopian
tube epithelium (FTE). Risk factors include germline mutations in breast cancer susceptibility …

Ovarian cancer is the second most common gynecologic cancer among women and the
second leading cause of death from gynecologic malignancy worldwide. Androgens, acting …

Combined oral contraceptives consist of the steroid hormone oestrogen in combination with
a progestogen, taken primarily to prevent pregnancy. The same hormones can also be used …