The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence

AD Gabbert, JL Mydosh, PK Talukdar, LM Gloss… - Biomolecules, 2023 - mdpi.com
Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide,
responsible for millions of cases of inflammatory diarrhea characterized by severe …

T6SS mediated stress responses for bacterial environmental survival and host adaptation

KW Yu, P Xue, Y Fu, L Yang - International journal of molecular sciences, 2021 - mdpi.com
The bacterial type VI secretion system (T6SS) is a protein secretion apparatus widely
distributed in Gram-negative bacterial species. Many bacterial pathogens employ T6SS to …

Manganese scavenging and oxidative stress response mediated by type VI secretion system in Burkholderia thailandensis

M Si, C Zhao, B Burkinshaw, B Zhang… - Proceedings of the …, 2017 - National Acad Sciences
Type VI secretion system (T6SS) is a versatile protein export machinery widely distributed in
Gram-negative bacteria. Known to translocate protein substrates to eukaryotic and …

A Pseudomonas aeruginosa type VI secretion system regulated by CueR facilitates copper acquisition

Y Han, T Wang, G Chen, Q Pu, Q Liu, Y Zhang… - PLoS …, 2019 - journals.plos.org
The type VI secretion system (T6SS) is widely distributed in Gram-negative bacteria, whose
function is known to translocate substrates to eukaryotic and prokaryotic target cells to cause …

Type VI Secretion System Transports Zn2+ to Combat Multiple Stresses and Host Immunity

T Wang, M Si, Y Song, W Zhu, F Gao, Y Wang… - PLoS …, 2015 - journals.plos.org
Type VI secretion systems (T6SSs) are widespread multi-component machineries that
translocate effectors into either eukaryotic or prokaryotic cells, for virulence or for …

Contact-independent killing mediated by a T6SS effector with intrinsic cell-entry properties

L Song, J Pan, Y Yang, Z Zhang, R Cui, S Jia… - Nature …, 2021 - nature.com
Bacterial type VI secretion systems (T6SSs) inject toxic effectors into adjacent eukaryotic and
prokaryotic cells. It is generally thought that this process requires physical contact between …

T6SS translocates a micropeptide to suppress STING-mediated innate immunity by sequestering manganese

L Zhu, L Xu, C Wang, C Li, M Li, Q Liu… - Proceedings of the …, 2021 - National Acad Sciences
Cellular ionic concentrations are a central factor orchestrating host innate immunity, but no
pathogenic mechanism that perturbs host innate immunity by directly targeting metal ions …

Pseudomonas aeruginosa T6SS-mediated molybdate transport contributes to bacterial competition during anaerobiosis

T Wang, X Du, L Ji, Y Han, J Dang, J Wen, Y Wang… - Cell reports, 2021 - cell.com
Type VI secretion system (T6SS) is widely distributed in Gram-negative bacteria and
functions as a versatile protein export machinery that translocates effectors into eukaryotic or …

Roles of type VI secretion system in transport of metal ions

X Yang, H Liu, Y Zhang, X Shen - Frontiers in Microbiology, 2021 - frontiersin.org
The type VI secretion system (T6SS) is a transmembrane protein nanomachine employed by
many gram-negative bacteria to directly translocate effectors into adjacent cells or the …

Type VI secretion system of Pseudomonas aeruginosa is associated with biofilm formation but not environmental adaptation

L Chen, Y Zou, AA Kronfl, Y Wu - Microbiologyopen, 2020 - Wiley Online Library
Pseudomonas aeruginosa encodes three type VI secretion systems (T6SSs), namely H1‐,
H2‐, and H3‐T6SS. P. aeruginosa hemolysin‐coregulated protein (Hcp) is the effector …