Structure–Activity Relationship Study and Design Strategies of Hydantoin, Thiazolidinedione, and Rhodanine-Based Kinase Inhibitors: A Two-Decade Review

M Naufal, E Hermawati, YM Syah, AT Hidayat… - ACS …, 2024 - ACS Publications
Cancer is one of the most prominent causes of the rapidly growing mortality numbers
worldwide. Cancer originates from normal cells that have acquired the capability to alter …

Step-economical photoassisted diversity-oriented synthesis: sustaining cascade photoreactions in oxalyl anilides to access complex polyheterocyclic molecular …

DM Kuznetsov, AG Kutateladze - Journal of the American …, 2017 - ACS Publications
Atom-and step-economy in photoassisted diversity-oriented synthesis (DOS) is achieved
with a versatile oxalyl linker offering rapid access to complex alkaloid mimics in very few …

Pharmacological applications of diphenylamine and its derivative as potent bioactive compound: A Review

A Kumar, AK Mishra - Current Bioactive Compounds, 2018 - ingentaconnect.com
In 1863, Diphenylamine (DPA) was prepared by Hoffmann by the destructive distillation of
different triphenylmethane dyes. DPA are naturally occurring compounds, present in onions …

Molecular modelling, cytotoxicity & biological investigation of novel fluorinated diphenylamine chalcone derivatives

A Shah, K Desai, A Bhanusali, N Malek, N Naik… - Journal of Molecular …, 2024 - Elsevier
Abstract A unique series of 1-(3-(3, 4-difluorophenyl) amino) phenyl) ethan-1-one linked
fluorinated diphenylamine chalcones (A1-A7) were synthesized and characterized by NMR …

Synthesis and antimicrobial activity of some new diphenylamine derivatives

A Kumar, AK Mishra - Journal of Pharmacy and Bioallied Sciences, 2015 - journals.lww.com
In search of new leads toward potent antimicrobial agent, an array of novel derivatives of 2-
hydrazinyl–NN, diphenyl acetamide has been synthesized from the chloroacetylation …

Intriguing multichannel photoinduced electron transfer in lanthanide (iii)–diphenylamine systems

P Verma, RM Sawant, H Pal - Physical Chemistry Chemical Physics, 2015 - pubs.rsc.org
Photoinduced electron transfer (PET) and charge transfer (CT) interactions of trivalent
lanthanide ions (Ln3+) with a fluorogenic diphenylamine (DPA) donor in aqueous solution …

Propofol affects EGF's activity in intestinal cell by down-regulating EGFR-mediated intracellular signaling

H Chai, W Peng, Z Zhu, D Xu, Y Chen… - Biological and …, 2021 - jstage.jst.go.jp
Propofol is a commonly used anesthetic drug in clinic. In recent years, a series of non-
anesthetic effects of propofol have been discovered. Studies have shown that propofol has …

Synthesis and biological evaluation of FJ-809, a compound originally described as MIM1 and an inhibitor of the anti-apoptotic protein Mcl-1

F Justaud, H Paysant, LB Weiswald, A Jebahi… - New Journal of …, 2022 - pubs.rsc.org
The development of inhibitors of anti-apoptotic proteins, such as Mcl-1, is currently a very
active area in the field of cancer research. One of the very first reported inhibitors of Mcl-1 …

Structural revision of the Mcl-1 inhibitor MIM1: synthesis and biological studies on ovarian cancer cells with evaluation of designed analogues

H Paysant, S Hedir, F Justaud, LB Weiswald… - Organic & …, 2021 - pubs.rsc.org
In the area of cancer research, the development of new and potent inhibitors of anti-
apoptotic proteins is a very active and promising topic. The small molecule MIM1 has been …

[HTML][HTML] ВЛИЯНИЕ ЭЛЕКТРОФИЛЬНЫХ СВОЙСТВ ГАЛОГЕНАРЕНОВ НА РЕГИОСЕЛЕКТИВНОСТЬ РЕАКЦИИ SNAR С БЕНЗОТРИАЗОЛОМ

АИ Хлопотинин, ЛВ Лобанова… - Башкирский химический …, 2022 - cyberleninka.ru
Исследовано влияние электрофильных свойств галогенаренов на региоселективность
реакции SNAr с бензотриазолом, в ходе которой происходит образование двух …