Background: Pollution–unwanted waste released to air, water, and land by human activity–is
the largest environmental cause of disease in the world today. It is responsible for an …

An emerging area in environmental toxicology is the role that chemicals and chemical
mixtures have on the cells of the human immune system. This is an important area of …

Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …

A number of recent studies have examined the functions of aryl hydrocarbon receptor (Ahr)
in the immune system. Also known as dioxin receptor, Ahr is a ligand-activated transcription …

Aryl hydrocarbon receptor (AHR) is thought to be a crucial factor in the regulation of immune
responses. Many AHR-mediated immunoregulatory mechanisms have been discovered …

Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that …

Simple Summary Cancer is driven by the excessive activity of growth-promoting genes and
deficient activity of the genes that restrain cell growth. Genes that suppress cell growth …

The impact of anthropogenic contaminants on the immune system of fishes is an issue of
growing concern. An important xenobiotic receptor that mediates effects of chemicals, such …

The skin, lung, and gut are important barrier organs that control how the body reacts to
environmental stressors such as ultraviolet (UV) radiation, air pollutants, dietary …

Environmental pollutants may cause adverse effects on the immune system of aquatic
organisms. However, the cellular effects of pollutants on fish immune system are largely …