[HTML][HTML] Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
Abstract Purpose This Position Paper aims to review and discuss the available data on
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
[HTML][HTML] Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics …
R Guilhaumou, S Benaboud, Y Bennis… - Critical Care, 2019 - Springer
Background Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the
intensive care unit (ICU). ICU patients present many pathophysiological features that cause …
intensive care unit (ICU). ICU patients present many pathophysiological features that cause …
[HTML][HTML] Rationalizing antimicrobial therapy in the ICU: a narrative review
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
Comprehensive guidance for antibiotic dosing in obese adults
L Meng, E Mui, MK Holubar… - … : The Journal of Human …, 2017 - Wiley Online Library
Physiologic alterations seen in obesity commonly impact the pharmacokinetics (PK) and
pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this …
pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this …
Towards precision medicine: Therapeutic drug monitoring–guided dosing of vancomycin and β-lactam antibiotics to maximize effectiveness and minimize toxicity
JA Cusumano, KP Klinker, A Huttner… - American Journal of …, 2020 - academic.oup.com
Purpose The goal of this review is to explore the role of antimicrobial therapeutic drug
monitoring (TDM), especially in critically ill, obese, and older adults, with a specific focus on …
monitoring (TDM), especially in critically ill, obese, and older adults, with a specific focus on …
[HTML][HTML] Therapeutic drug monitoring-guided continuous infusion of piperacillin/tazobactam significantly improves pharmacokinetic target attainment in critically ill …
DC Richter, O Frey, A Röhr, JA Roberts, A Köberer… - Infection, 2019 - Springer
Purpose Standard dosing and intermittent bolus application (IB) are important risk factors for
pharmacokinetic (PK) target non-attainment during empirical treatment with β-lactams in …
pharmacokinetic (PK) target non-attainment during empirical treatment with β-lactams in …
Ten-day vonoprazan-amoxicillin dual therapy as a first-line treatment of Helicobacter pylori infection compared with bismuth-containing quadruple therapy
HS Qian, WJ Li, YN Dang, LR Li, XB Xu… - Official journal of the …, 2023 - journals.lww.com
METHODS: A total of 375 treatment-naive, H. pylori-infected subjects were randomly
assigned in a 1: 1: 1 ratio into 3 regimen groups including VHA-dual (vonoprazan 20 mg …
assigned in a 1: 1: 1 ratio into 3 regimen groups including VHA-dual (vonoprazan 20 mg …
Simultaneous quantification of cefepime, meropenem, ciprofloxacin, moxifloxacin, linezolid and piperacillin in human serum using an isotope-dilution HPLC–MS/MS …
M Paal, M Zoller, C Schuster, M Vogeser… - … of pharmaceutical and …, 2018 - Elsevier
The aim of the current study was to develop and validate a robust multi-analyte high
performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS) method for …
performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS) method for …
[HTML][HTML] Pharmacokinetics, pharmacodynamics, and dosing considerations of novel β-lactams and β-lactam/β-lactamase inhibitors in critically ill adult patients: focus …
D Bakdach, R Elajez, AR Bakdach, A Awaisu… - Journal of Clinical …, 2022 - mdpi.com
Objective: Dose optimization of novel β-lactam antibiotics (NBLA) has become necessary
given the increased prevalence of multidrug-resistant infections in intensive care units …
given the increased prevalence of multidrug-resistant infections in intensive care units …
Therapeutic drug monitoring of beta-lactam antibiotics–Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC …
N Pinder, T Brenner, S Swoboda, MA Weigand… - … of pharmaceutical and …, 2017 - Elsevier
Introduction Therapeutic drug monitoring (TDM) is a useful tool to optimize antibiotic therapy.
Increasing interest in alternative dosing strategies of beta-lactam antibiotics, eg continuous …
Increasing interest in alternative dosing strategies of beta-lactam antibiotics, eg continuous …