[HTML][HTML] Intracellular and extracellular lipopolysaccharide signaling in sepsis: avenues for novel therapeutic strategies

RS Gabarin, M Li, PA Zimmel, JC Marshall… - Journal of innate …, 2021 - karger.com
Sepsis is defined as organ dysfunction due to a dysregulated systemic host response to
infection. During gram-negative bacterial infection and other acute illness such as …

Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID‐19 prevention and cure

MN Islam, KS Hossain, PP Sarker… - Phytotherapy …, 2021 - Wiley Online Library
Nigella sativa seed and its active compounds have been historically recognized as an
effective herbal panacea that can establish a balanced inflammatory response by …

Programmed cell death in sepsis associated acute kidney injury

Z Wu, J Deng, H Zhou, W Tan, L Lin, J Yang - Frontiers in Medicine, 2022 - frontiersin.org
Sepsis-associated acute kidney injury (SA-AKI) is common in patients with severe sepsis,
and has a high incidence rate and high mortality rate in ICU patients. Most patients progress …

Thymoquinone: A promising natural compound with potential benefits for COVID-19 prevention and cure

OA Badary, MS Hamza, R Tikamdas - Drug design, development …, 2021 - Taylor & Francis
COVID-19 has caused a major global health crisis, as excessive inflammation, oxidation,
and exaggerated immune response in some sufferers can lead to a condition known as …

Using green biosynthesized lycopene-coated selenium nanoparticles to rescue renal damage in glycerol-induced acute kidney injury in rats

A Al-Brakati, KF Alsharif, KJ Alzahrani… - International journal …, 2021 - Taylor & Francis
Purpose Selenium nanoparticles (SeNPs) have recently gained much attention in
nanomedicine applications owing to their unique biological properties. Biosynthesis of …

Protective Effects of Black Cumin (Nigella sativa) and Its Bioactive Constituent, Thymoquinone against Kidney Injury: An Aspect on Pharmacological Insights

MA Hannan, MS Zahan, PP Sarker, A Moni… - International Journal of …, 2021 - mdpi.com
The prevalence of chronic kidney disease (CKD) is increasing worldwide, and a close
association between acute kidney injury (AKI) and CKD has recently been identified. Black …

Polyphenols are potential nutritional adjuvants for targeting COVID‐19

MA El‐Missiry, A Fekri, LA Kesar… - Phytotherapy …, 2021 - Wiley Online Library
The newly emerging severe acute respiratory syndrome, coronavirus‐2 (SARS‐CoV‐2) is a
dangerous pathogen that causes global health problems. It causes a disease called …

The programmed cell death of macrophages, endothelial cells, and tubular epithelial cells in sepsis-AKI

C Li, W Wang, S Xie, W Ma, Q Fan, Y Chen, Y He… - Frontiers in …, 2021 - frontiersin.org
Sepsis is a systemic inflammatory response syndrome caused by infection, following with
acute injury to multiple organs. Sepsis-induced acute kidney injury (AKI) is currently …

Effect of saffron, black seed, and their main constituents on inflammatory cytokine response (mainly TNF-α) and oxidative stress status: An aspect on pharmacological …

Z Vafaeipour, M Ghasemzadeh Rahbardar… - Naunyn-Schmiedeberg's …, 2023 - Springer
Tumor necrosis factor-α (TNF-α), an inflammatory cytokine, is produced by monocytes and
macrophages. It is known as a'double-edged sword'because it is responsible for …

Plants' bioactive secondary metabolites in the management of sepsis: Recent findings on their mechanism of action

MF Mahomoodally, MZ Aumeeruddy… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a severe inflammatory response to systemic infection and is a threatening cause of
death in intensive care units. In recent years, a number of studies have been conducted on …