Highlights•CCS distributions and shifts contain valuable information about
analytes.•Compound-dependent effects of gas, field and temperature explain calibration …

Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …

Specific molecular recognition is assumed to require a well-defined set of contacts and
devoid of conformational and interaction ambiguities. Growing experimental evidence …

Highlights•Intrinsically disordered proteins mostly function by molecular recognition.•Post-
translational modifications regulate the interactions of IDPs.•Structural disorder can facilitate …

In this Review, we focus on an important aspect of ion mobility (IM) research, namely, the
reporting of quantitative ion mobility measurements in the form of the gas-phase collision …

The last∼ 25 years has seen mass spectrometry (MS) emerge as an integral method in the
structural biology toolkit. In particular, MS has enabled the structural characterization of …

Negative-stranded RNA viruses (NSVs) are important human pathogens, including
emerging and reemerging viruses that cause respiratory, hemorrhagic and other severe …

Entire functional proteins as well as large regions of proteins lack structural elements which
are resolvable via crystallography or NMR. These intrinsically disordered proteins (IDPs) or …

In this review, we detail the most common experimental approaches to assess and
characterize protein intrinsic structural disorder, with the notable exception of NMR and EPR …

Intrinsically disordered proteins (IDPs) are systematically under‐represented in structural
proteomics studies. Their structural characterization implies description of the dynamic …