Obesity constitutes one of the most important metabolic diseases being associated to insulin
resistance development and increased cardiovascular risk. Association between obesity …

Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in
obesity. Leptin exerts many different actions on various tissues and systems, including …

Esophageal adenocarcinoma (EAC) has one of the fastest increases in incidence of any
cancer, along with poor five-year survival rates. Barrett's esophagus (BE) is the main risk …

The aim of the study was the investigation of relationship between cachexia syndrome and
serum resistin, adiponectin, and apelin in patients with gastroesophageal cancer (GEC) …

Objective To clarify the prognostic role of tumour protein 53 (TP53) mutations in patients with
oesophageal adenocarcinoma (OAC) as there is a need for biomarkers that assist in guiding …

Wnt signaling was initially recognized to be vital for tissue development and homeostasis
maintenance. Further studies revealed that this pathway is also important for tumorigenesis …

Esophageal adenocarcinoma (EAC) is still associated with poor prognosis, despite modern
multi-modal therapies. New molecular markers, which control cell cycle and promote lymph …

Background & Aims Metabolically active visceral fat may be associated with esophageal
inflammation, metaplasia, and neoplasia. We performed a meta-analysis to evaluate the …

An exponential increase in the prevalence of obesity has been observed in the United
States in recent decades, 1 paralleled by a comparable increase in the incidence of …

Background Esophageal cancer is the most common cause of cancer-related death
worldwide with a diverse geographical distribution, poor prognosis, and diagnosis in …