[HTML][HTML] Current perspectives on the beneficial effects of soybean isoflavones and their metabolites for humans

IS Kim - Antioxidants, 2021 - mdpi.com
Soybeans are rich in proteins and lipids and have become a staple part of the human diet.
Besides their nutritional excellence, they have also been shown to contain various functional …

Diet, microorganisms and their metabolites, and colon cancer

SJD O'keefe - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
Colorectal cancer is one of the so-called westernized diseases and the second leading
cause of cancer death worldwide. On the basis of global epidemiological and scientific …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

[HTML][HTML] Lipid metabolism, disorders and therapeutic drugs–review

V Natesan, SJ Kim - Biomolecules & therapeutics, 2021 - ncbi.nlm.nih.gov
Different lifestyles have an impact on useful metabolic functions, causing disorders. Different
lipids are involved in the metabolic functions that play various vital roles in the body, such as …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

[HTML][HTML] The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

JV van Vliet-Ostaptchouk, ML Nuotio, SN Slagter… - BMC endocrine …, 2014 - Springer
Background Not all obese subjects have an adverse metabolic profile predisposing them to
developing type 2 diabetes or cardiovascular disease. The BioSHaRE-EU Healthy Obese …

[HTML][HTML] Obesity and cancer: existing and new hypotheses for a causal connection

TW Stone, M McPherson, LG Darlington - EBioMedicine, 2018 - thelancet.com
Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of
dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

[HTML][HTML] Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma

DW Jeong, JW Park, KS Kim, J Kim, J Huh… - Nature …, 2023 - nature.com
Palmitic acid (PA) is the most common fatty acid in humans and mediates palmitoylation
through its conversion into palmitoyl coenzyme A. Although palmitoylation affects many …