Aqueous prostaglandin eye drop formulations
P Jansook, T Loftsson - Pharmaceutics, 2022 - mdpi.com
Glaucoma is one of the leading causes of irreversible blindness worldwide. It is
characterized by progressive optic neuropathy in association with damage to the optic nerve …
characterized by progressive optic neuropathy in association with damage to the optic nerve …
Recently approved drugs for lowering and controlling intraocular pressure to reduce vision loss in ocular hypertensive and glaucoma patients
NA Sharif - Pharmaceuticals, 2023 - mdpi.com
Serious vision loss occurs in patients affected by chronically raised intraocular pressure
(IOP), a characteristic of many forms of glaucoma where damage to the optic nerve …
(IOP), a characteristic of many forms of glaucoma where damage to the optic nerve …
[HTML][HTML] A novel fixed-combination timolol-netarsudil-latanoprost ophthalmic solution for the treatment of glaucoma and ocular hypertension
T Wang, Y Zhang, M Chi, C Zhao, L Cao, C Tian… - Asian Journal of …, 2022 - Elsevier
Currently commercial fixed-concomitant three agents have multiple problems such as
multiple dosing administration, poor efficacy and side effects. Once-daily fixed-combination …
multiple dosing administration, poor efficacy and side effects. Once-daily fixed-combination …
The role of conventional and unconventional adaptive routes in lowering of intraocular pressure: Theoretical model and simulation
R Sacco, G Chiaravalli, G Antman, G Guidoboni… - Physics of …, 2023 - pubs.aip.org
In this article, we propose a theoretical model leveraging the analogy between fluid and
electric variables to investigate the relation among aqueous humor (AH) circulation and …
electric variables to investigate the relation among aqueous humor (AH) circulation and …
How latanoprost changed glaucoma management
MF Cordeiro, S Gandolfi, K Gugleta… - Acta …, 2024 - Wiley Online Library
Glaucoma is currently considered one of the leading causes of severe visual impairment
and blindness worldwide. Topical medical therapy represents the treatment of choice for …
and blindness worldwide. Topical medical therapy represents the treatment of choice for …
Effect of a fixed combination of ripasudil and brimonidine on aqueous humor dynamics in mice
R Yamagishi-Kimura, M Honjo, M Aihara - Scientific Reports, 2024 - nature.com
Ripasudil–brimonidine fixed-dose combination (K-232) simultaneously targets three
different intraocular pressure (IOP) lowering mechanisms, increasing trabecular meshwork …
different intraocular pressure (IOP) lowering mechanisms, increasing trabecular meshwork …
[HTML][HTML] Advancing ophthalmic delivery of flurbiprofen via synergistic chiral resolution and ion-pairing strategies
Z Ma, Y Wang, H He, T Liu, Q Jiang, X Hou - Asian Journal of …, 2024 - Elsevier
Flurbiprofen (FB), a nonsteroidal anti-inflammatory drug, is widely employed in treating
ocular inflammation owing to its remarkable anti-inflammatory effects. However, the racemic …
ocular inflammation owing to its remarkable anti-inflammatory effects. However, the racemic …
Modification of contact lenses via metal‐organic frameworks for glaucoma treatment
The prevention of blindness from glaucoma requires multiple treatments to lower intraocular
pressure. Here, human contact lenses are modified with highly porous metal‐organic …
pressure. Here, human contact lenses are modified with highly porous metal‐organic …
Currently available prostanoids for the treatment of glaucoma and ocular hypertension: A review
B Benitez, AM Anter, J Arcuri… - Current opinion in …, 2024 - Elsevier
Recent advancements in prostaglandin analogs (PGAs) have reinforced their role in
managing intraocular pressure (IOP). Latanoprost excels in 24-h IOP control, while various …
managing intraocular pressure (IOP). Latanoprost excels in 24-h IOP control, while various …
Electrosprayed core-shell nanoparticles for sustained release fixed combination monotherapy in glaucoma treatment
Glaucoma, leading to progressive partial or complete blindness, is a matter of serious
concern worldwide. Although avoidable with right diagnosis and continuous treatment, a …
concern worldwide. Although avoidable with right diagnosis and continuous treatment, a …