Increasing antibiotic resistance in multidrug-resistant (MDR) Gram-negative bacteria (MDR-
GNB) presents significant health problems worldwide, since the vital available and effective …

Multidrug resistance in Escherichia coli has become a worrying issue that is increasingly
observed in human but also in veterinary medicine worldwide. E. coli is intrinsically …

Bacterial antimicrobial resistance (AMR) is constantly evolving and horizontal gene transfer
through plasmids plays a major role. The identification of plasmid characteristics and their …

Colistin has been extensively used since the middle of the last century in animals,
particularly in swine, for the control of enteric infections. Colistin is presently considered the …

Polymyxins are well-established antibiotics that have recently regained significant interest
as a consequence of the increasing incidence of infections due to multidrug-resistant Gram …

Colistin represents one of the few available drugs for treating infections caused by
carbapenem-resistant Enterobacteriaceae. As such, the recent plasmid-mediated spread of …

Colistin is an effective antibiotic for treatment of most multidrug-resistant Gram-negative
bacteria. It is used currently as a last-line drug for infections due to severe Gram-negative …

Colistin, also referred to as polymyxin E, is an effective antibiotic against most multidrug-
resistant Gram-negative bacteria and is currently used as a last-line drug for treating severe …

Post-weaning diarrhea (PWD) is one of the most serious threats for the swine industry
worldwide. It is commonly associated with the proliferation of enterotoxigenic Escherichia …

Polymyxins have recently been re-introduced into the therapeutic arsenal to combat
infections caused by multidrug-resistant Gram-negative bacteria. However, the emergence …