Role of mitochondria in pathogenesis and therapy of renal fibrosis
X Zhao, Y Li, J Yu, H Teng, S Wu, Y Wang, H Zhou, F Li - Metabolism, 2024 - Elsevier
Renal fibrosis, specifically tubulointerstitial fibrosis, represents the predominant pathological
consequence observed in the context of progressive chronic kidney conditions. The …
consequence observed in the context of progressive chronic kidney conditions. The …
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction
J Feng, Y Li, Y Zhang, S Sun, J Sun, Q Xu, X Ji… - Journal of Translational …, 2024 - Springer
Background The autophagy adapter SQSTM1/p62 is crucial for maintaining homeostasis in
various organs and cells due to its protein–protein interaction domains and involvement in …
various organs and cells due to its protein–protein interaction domains and involvement in …
Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in …
X Gao, B Lin, C Chen, Z Fang, J Yang, S Wu… - Food & Function, 2024 - pubs.rsc.org
Several mechanisms underlying nephrolithiasis, one of the most common urological
diseases, involve calcium oxalate formation, including oxidative stress, inflammatory …
diseases, involve calcium oxalate formation, including oxidative stress, inflammatory …
Targeted inhibition of transforming growth factor-β type I receptor by AZ12601011 improves paraquat poisoning-induced multiple organ fibrosis
H Zhang, H Yang, X Liu, J Ying, T Zu, J Jiang… - Pesticide Biochemistry …, 2024 - Elsevier
Paraquat (PQ) causes fatal poisoning that leads to systemic multiple organ fibrosis, and
transforming growth factor (TGF)-β1 plays a critical role in this process. In this study, we …
transforming growth factor (TGF)-β1 plays a critical role in this process. In this study, we …
Isolation and target identification of anti-renal fibrosis compounds from Cordyceps militaris
W Yang, KF Zhu, CT Tao, YM Yan, YX Cheng - Bioorganic Chemistry, 2024 - Elsevier
Four undescribed compounds including one aromatic glucoside derivative,
cordyceglycoside A (1), one new isoleucine derivative inner salt, cordycepisosalt A (2), a …
cordyceglycoside A (1), one new isoleucine derivative inner salt, cordycepisosalt A (2), a …
Lycopene inhibits apoptosis of mouse spermatocytes in varicocele via miR-23a/b-induced downregulation of PROK2
H Wang, B Zhu, T Jing, L Yu, K Zhang… - Reproduction, Fertility …, 2024 - CSIRO Publishing
Context. The varicocele is the leading cause of male infertility and can impair sperm quality
and testicular function through various mechanisms. In our previous study, we found the …
and testicular function through various mechanisms. In our previous study, we found the …