Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

History of inflammatory bowel diseases

GC Actis, R Pellicano, S Fagoonee… - Journal of clinical …, 2019 - mdpi.com
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the
intestinal mucosa and unknown etiology. In this review, we identified three main eras in the …

Inflammatory bowel disease: tri-directional relationship between microbiota, immune system and intestinal epithelium

S Ahlawat, P Kumar, H Mohan, S Goyal… - Critical Reviews in …, 2021 - Taylor & Francis
Human gut microbiota contributes to host nutrition and metabolism, sustains intestinal cell
proliferation and differentiation, and modulates host immune system. The alterations in their …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

Inflammatory bowel diseases and Parkinson's disease

T Brudek - Journal of Parkinson's disease, 2019 - content.iospress.com
The etiology of Parkinson's disease (PD) is multifactorial, with genetics, aging, and
environmental agents all a part of the PD pathogenesis. Widespread aggregation of the α …

[HTML][HTML] Precision medicine in inflammatory bowel disease: concept, progress and challenges

SP Borg-Bartolo, RK Boyapati, J Satsangi… - F1000Research, 2020 - ncbi.nlm.nih.gov
Crohn's disease and ulcerative colitis are increasingly prevalent, relapsing and remitting
inflammatory bowel diseases (IBDs) with variable disease courses and complications. Their …

Role of the gut–brain axis, gut microbial composition, diet, and probiotic intervention in Parkinson's disease

S Thangaleela, BS Sivamaruthi, P Kesika, M Bharathi… - Microorganisms, 2022 - mdpi.com
Parkinson's disease (PD) is the second-most prevalent neurodegenerative or
neuropsychiatric disease, affecting 1% of seniors worldwide. The gut microbiota (GM) is one …

Polystyrene microplastics induce an immunometabolic active state in macrophages

SD Merkley, HC Moss, SM Goodfellow, CL Ling… - Cell biology and …, 2022 - Springer
Anti-inflammatory and proinflammatory responses in macrophages are influenced by
cellular metabolism. Macrophages are the primary phagocyte in mucosal environments (ie …

Trends in the use of biologicals and their treatment outcomes among patients with inflammatory bowel diseases–a Danish nationwide cohort study

M Zhao, M Sall Jensen, T Knudsen… - Alimentary …, 2022 - Wiley Online Library
Background Therapeutic management of inflammatory bowel diseases (IBD) is rapidly
evolving, with an expanding armoury of biological drugs at our disposal. However, real …

Long non-coding RNAs and their “discrete” contribution to IBD and Johne's disease—what stands out in the current picture? A comprehensive review

KA Triantaphyllopoulos - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-coding RNAs (ncRNA) have paved the way to new perspectives on the regulation of
gene expression, not only in biology and medicine, but also in associated fields and …