Objectives Besides CD4 regulatory T-cells (Tregs), immunosuppressor FoxP3+ CD8 T-cells
are emerging as an important subset of Tregs, which contribute to immune dysfunction and …

Simple Summary Oncoviruses are viruses with oncogenic potential, responsible for almost
20% of human cancers worldwide. They are from various families, some of which belong to …

Backgrounds: The tissue resident memory CD8 T cell (Trm) constitutes an important
component of the local immunity. In the context of malignant tumors, mounting evidence also …

Chimeric antigen receptor (CAR) T cell therapy has transformed cancer immunotherapy.
However, significant challenges limit its application beyond B cell-driven malignancies …

Despite significant progress in modern medicine and pharmacology, damage to the nervous
system with various etiologies still poses a challenge to doctors and scientists. Injuries lead …

Chemokine G-protein coupled receptors are validated drug targets for many diseases,
including cancer, neurological, and inflammatory disorders. Despite much time and effort …

OBJECTIVE: Thymus is an immune organ in which pathological changes may cause
autoimmune diseases, including myasthenia gravis (MG). Recent studies have focused on …

Background and Objectives: Most published research has only investigated a single
timepoint after the onset of severe acute pancreatitis (SAP), meaning that they have been …

Adult T-cell leukemia/lymphoma (ATL) is triggered by infection with human T-cell
lymphotropic virus-1 (HTLV-1). Here, we describe the reprogramming of pyrimidine …

The balance among different CD4+ T cell subsets is crucial for repairing the injured spinal
cord. Dendritic cell (DC)‐derived small extracellular vesicles (DsEVs) effectively activate T …