Advances in glycoside and oligosaccharide synthesis

CJ Crawford, PH Seeberger - Chemical Society Reviews, 2023 - pubs.rsc.org
The structural complexity of glycans poses a serious challenge in the chemical synthesis of
glycosides, oligosaccharides and glycoconjugates. Glycan complexity, determined by …

Recent chemical synthesis of plant polysaccharides

X Wang, G Xiao - Current Opinion in Chemical Biology, 2023 - Elsevier
Here, chemical syntheses of long, branched and complex glycans over 10-mer from plants
are summarized, which highlights amylopectin 20-mer from starch, 17-mer from carthamus …

Chemical synthesis of polysaccharides

S Wang, Y Yang, Q Zhu, GQ Lin, B Yu - Current Opinion in Chemical …, 2022 - Elsevier
Here we summarize the chemical syntheses of glycans containing over 20 monosaccharide
units, with the recent syntheses of ultra-long glycans, including a 92mer arabinogalactan, a …

Chemical Synthesis of the Highly Sterically Hindered Core Undecasaccharide of Helicobacter pylori Lipopolysaccharide for Antigenicity Evaluation with Human …

X Zou, J Hu, M Zhao, C Qin, Y Zhu, G Tian… - Journal of the …, 2022 - ACS Publications
Helicobacter pylori, listed as a human carcinogen by the Department of Health and Human
Services, colonizes the gastric mucosa of more than half of the world's population. The …

One-Pot Assembly of Mannose-Capped Lipoarabinomannan Motifs up to 101-Mer from the Mycobacterium tuberculosis Cell Wall

Y Ma, Y Zhang, Y Huang, Z Chen, Q Xian… - Journal of the …, 2024 - ACS Publications
Lipoarabinomannan (LAM) from the Mycobacterium tuberculosis cell envelope represents
important targets for the development of new therapeutic agents against tuberculosis, which …

Modular Synthesis of a Tridecasaccharide Motif of Bacteroides vulgatus Lipopolysaccharides against Inflammatory Bowel Diseases through an Orthogonal One‐Pot …

Y Zhang, L Wang, Q Zhou, Z Li, D Li… - Angewandte Chemie …, 2023 - Wiley Online Library
Lipopolysaccharides from Bacteroides vulgatus represent interesting targets for the
treatment of inflammatory bowel diseases. However, efficient access to long, branched and …

Dendrobium huoshanense CZTang et SJCheng: A Review of Its Traditional Uses, Phytochemistry, and Pharmacology

L Gao, F Wang, T Hou, C Geng, T Xu, B Han… - Frontiers in …, 2022 - frontiersin.org
Dendrobium huoshanense, a traditional medicinal and food homologous plant, belongs to
the family Orchidaceae and has a long history of medicinal use. It is reported that the stem of …

Chemical Synthesis and Antigenicity Evaluation of Shigella dysenteriae Serotype 10 O-Antigen Tetrasaccharide Containing a (S)-4,6-O-Pyruvyl Ketal

C Qin, L Li, G Tian, M Ding, S Zhu, W Song… - Journal of the …, 2022 - ACS Publications
Shigella is the second most common etiologic pathogen responsible for childhood acute
diarrhea. An anti-Shigella vaccine is still eagerly awaited due to the increasing drug …

Recent advances in stereoselective 1,2-cis-O-glycosylations

A Ishiwata, K Tanaka, J Ao, F Ding, Y Ito - Frontiers in Chemistry, 2022 - frontiersin.org
For the stereoselective assembly of bioactive glycans with various functions, 1, 2-cis-O-
glycosylation is one of the most essential issues in synthetic carbohydrate chemistry. The cis …

Highly stereoselective α-glycosylation with GalN 3 donors enabled collective synthesis of mucin-related tumor associated carbohydrate antigens

K Shou, Y Zhang, Y Ji, B Liu, Q Zhou, Q Tan, F Li… - Chemical …, 2024 - pubs.rsc.org
Mucin-related tumor-associated carbohydrate antigens (TACAs) are important and
interesting targets for cancer vaccine therapy. However, efficient access to a library of mucin …